Featured Publications
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development.
Karner CM, Das A, Ma Z, Self M, Chen C, Lum L, Oliver G, Carroll TJ Development 2011 Apr 138 7 1247-57
Tankyrase is necessary for canonical Wnt signaling during kidney development.
Karner CM, Merkel CE, Dodge M, Ma Z, Lu J, Chen C, Lum L, Carroll TJ Dev. Dyn. 2010 Jul 239 7 2014-23
Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesis.
Karner CM, Chirumamilla R, Aoki S, Igarashi P, Wallingford JB, Carroll TJ. Nature Genetics July 2009 41(7) 793-799
Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state.
Marose TD, Merkel CE, McMahon AP, Carroll TJ. Dev. Biol. February 2008 314(1) 112-26
Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system.
Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP. Developmental Cell August 2005 9 (2) 283-92
The Leucine Zipper Putative Tumor Suppressor 2 Protein LZTS2 Regulates Kidney Development.
Peng Y, Clark C, Luong R, Tu WH, Lee J, Johnson DT, Das A, Carroll TJ, Sun Z J. Biol. Chem. 2011 Nov 286 46 40331-42
PCP goes organic.
Carroll TJ Organogenesis 2011 Jul 7 3 163-4
Planar cell polarity in kidney development and disease.
Carroll TJ, Das A Organogenesis 2011 Jul 7 3 180-90
Integrin-linked kinase regulates p38 MAPK-dependent cell cycle arrest in ureteric bud development.
Smeeton J, Zhang X, Bulus N, Mernaugh G, Lange A, Karner CM, Carroll TJ, Fässler R, Pozzi A, Rosenblum ND, Zent R Development 2010 Oct 137 19 3233-43
Macrophage Wnt7b is critical for kidney repair and regeneration.
Lin SL, Li B, Rao S, Yeo EJ, Hudson TE, Nowlin BT, Pei H, Chen L, Zheng JJ, Carroll TJ, Pollard JW, McMahon AP, Lang RA, Duffield JS Proc. Natl. Acad. Sci. U.S.A. 2010 Mar 107 9 4194-9