Michael Story, Ph.D.

Associate Professor

Department: Radiation Oncology

Graduate Programs: Cancer Biology

Education

Undergraduate Colorado State University (), Biochemistry
Graduate School Colorado State University (1989)

Research Interests

  • Carcinogenesis associated with HZE particle exposure
  • Intrinsic radiosensitivity
  • Modulation of drug and radiation response by GSTO expression
  • molecular markers of radioresponse
  • Radiotherapy research: SBRT and other

Publications

Featured Publications Legend

Featured Publications

Elimination of the differential chemoresistance between the murine B-cell lymphoma LY-ar and LY-as cell lines after arsenic (As2O3) exposure via the overexpression of GSTO1 (p28). .

Giri, U., Terry, N. H. A., Story, M.D. Cancer Chemother Pharmacol 2005 55 511-521

Adenoviral-mediated mda-7 expression suppresses DNA repair capacity and radiosensitizes non-small cell lung cancer cells.

Nishikawa, T., Munshi, A., Story, M.D., Ismail, S., Stevens, C., Chada, S., and Meyn, R.E. Oncogene 2004 23 7125-7131

A Ser49Cys variant in the ataxia telangiectasia, mutated (ATM) gene that is more common in breast cancer patients compared to population controls.

Buchholz, T. A., Weil, M. M., Ashorn, C. L., Strom, E. A., Sigurdson, A., Bondy, M., Chakraborty, R., Cox, J. D., McNeese, M. D., and Story, M.D. Cancer 2004 100 1345-1351

Predicting radiosensitivity using DNA end-binding complex analysis.

Ismail, S.M., Puppi, M., Prithivirasingh, S., Raju, U., Meyn, R. E., Buchholz, T. A., Story, M.D., Brock, W.A., Milas, M., Thames, H. D., and Stevens, C.W. Clin. Cancer Res. 2004 10 1226-1234

Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.

Zhang, X, Succi, J, Feng, Z, Prithivirajsingh, S, Story, M.D. and Legerski, R.J. Molec. Cell Biol 2004 24 9207-9220

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Honors/Awards

  • NCI Predoctoral Trainee
    (1983)

Professional Associations/Affiliations

  • American Association for Cancer Research
  • Federation of American Societies for Experimental Biology
  • Radiation Research Society