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Steven Vernino, M.D.,  Ph.D.

Steven Vernino, M.D., Ph.D.

Vice Chair for Education & Faculty Affairs

Professor

Endowed Title
Distinguished Teaching Professor; Dr. Bob and Jean Smith Foundation Distinguished Chair in Neuromuscular Disease Research; Rex Griswold Distinguished Professorship in Multiple System Atrophy
School
Medical School
Department
Neurology

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Joined UT Southwestern: 2004

    Steven Vernino, M.D., Ph.D., is a Distinguished Teaching Professor and Vice Chair for Education and Faculty Affairs in the Department of Neurology at UT Southwestern Medical Center.

    Clinical Interests: Dr. Vernino specializes in evaluating, diagnosing, and treating autoimmune neurological disorders, autonomic disorders, and neuromuscular disorders.  He is board certified in neurology, neuromuscular medicine, and autonomic disorders.  He is the founding Director of the multidisciplinary Multiple System Atrophy (MSA) Clinic, (which is designated as a Clinical Center of Excellence by the MSA Coaltion), and the Autonomic Disorders Clinic and Laboratory.  He has specific clinical interests in multiple system atrophy, pure autonomic failure, autoimmune autonomic disorders, postural tachycardia syndrome (POTS), myasthenia gravis, paraneoplastic neurological disorders and autoimmune encephalitis. 

    Research:  Dr. Vernino has helped define the relationship between autoimmune disorders and disorders of the autonomic nervous system and identified the antibodies to ganglionic acetylcholine receptors as the cause of autoimmune autonomic ganglionopathy, a rare autonomic nervous system disorder. He has also characterized several neurological antibodies related to paraneoplastic disorders.  He has published more than 120 peer-reviewed articles and dozens of book chapters and reviews.

    Trainee Education:  Dr. Vernino is active in teaching medical students, residents and fellows.  He served as neurology residency program director at UT Southwestern for 11 years.  He is director of the Autonomic Disorders Fellowship Program which is accredited by the UCNS.

    Affiliations & Awards:
    Among his many professional activities, Dr. Vernino serves on the Board of Directors of the American Autonomic Society and served as the president of AAS from 2020-2022.  He also serves on the medical advisory boards of the Myasthenia Gravis Foundation of America, Multiple System Atrophy Coalition, and Dysautonomia International. Dr. Vernino has been named as a Fellow of the American Academy of Neurology, the American Neurological Association and the American Autonomic Society.  

    He has received numerous awards for his work as a clinician, researcher, and teacher, including the 1998 American Academy of Neurology (AAN) Founders Award, the 2013 AAN Program Director Recognition Award, and the 2018 University of Texas Regents Outstanding Teacher Award. He was inducted into the Southwestern Academy of Teachers in 2015.

  • Education
    Other Post Graduate Training
    Baylor College of Medicine (1992)
    Graduate School
    Baylor College of Medicine (1992)
    Medical School
    Baylor College of Medicine (1994)
    Internship
    Mayo Clinic (1995), Internal Medicine
    Residency
    Mayo Clinic (1998), Neurology
    Fellowship
    Mayo Clinic (1999), Neuroimmunology
  • Research Interest
    • Care models, diagnosis, and emerging treatments for multiple system atrophy (MSA)
    • Clinical phenotyping and outcome measure development for postural tachycardia syndrome (POTS)
    • Clinical treatment trials for autoimmune and autonomic disorders
    • Paraneoplastic neurological syndromes
  • Publications
    Phenoconversion in pure autonomic failure: a multicentre prospective longitudinal cohort study
    Vernetti PM, Norcliffe-Kaufmann L, Palma JA, Biaggioni I, Shibao CA, Peltier A, Freeman R, Gibbons C, Goldstein DS, Low PA, Singer W, Coon EA, Miglis MG, Wenning GK, Fanciulli A, Vernino S, Betensky RA, Kaufmann H Brain 2024 Jul 147 2440-2448
    Effect of Lower Extremity Nerve Decompression in Patients With Painful Diabetic Peripheral Neuropathy: The Diabetic Neuropathy Nerve Decompression Randomized, Observation Group and Placebo Surgery-Controlled Clinical Trial
    Rozen SM, Wolfe GI, Vernino S, Raskin P, Hynan LS, Wyne K, Fulmer R, Pandian G, Sharma SK, Mohanty AJ, Sanchez CV, Hembd A, Gorman A Annals of surgery 2024 Jul 280 35-45
    Randomized controlled trial of intravenous immunoglobulin for autoimmune postural orthostatic tachycardia syndrome (iSTAND)
    Vernino S, Hopkins S, Bryarly M, Hernandez RS, Salter A Clinical Autonomic Research 2024 Feb 34 153-163
    Paraneoplastic autonomic neuropathies and GI dysmotility
    Golden E, Vernino S 2024 Jan 275-282
    Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients with Synucleinopathies
    Gibbons CH, Levine T, Adler C, Bellaire B, Wang N, Stohl J, Agarwal P, Aldridge GM, Barboi A, Evidente VG, Galasko D, Geschwind MD, Gonzalez-Duarte A, Gil R, Gudesblatt M, Isaacson SH, Kaufmann H, Khemani P, Kumar R, Lamotte G, Liu AJ, McFarland NR, Miglis M, Reynolds A, Sahagian GA, Saint-Hillaire MH, Schwartzbard JB, Singer W, Soileau MJ, Vernino S, Yerstein O, Freeman R JAMA 2024 331 1298-1306
    VH2+ Antigen-Experienced B Cells in the Cerebrospinal Fluid Are Expanded and Enriched in Pediatric Anti-NMDA Receptor Encephalitis
    Monson N, Smith C, Greenberg H, Plumb P, Guzman A, Tse K, Chen D, Zhang W, Morgan M, Speed H, Powell C, Batra S, Cowell L, Christley S, Vernino S, Blackburn K, Greenberg B Journal of Immunology 2023 Nov 211 1332-1339
    Saturation mutagenesis of α-synuclein reveals monomer fold that modulates aggregation
    Chlebowicz J, Russ W, Chen D, Vega A, Vernino S, White CL, Rizo J, Joachimiak LA, Diamond MI Science Advances 2023 Oct 9
    The need for consistent clinical definitions in autonomic medicine
    Vernino S Clinical Autonomic Research 2023 Jun 33 215-216
    Autoimmune Encephalitis Misdiagnosis in Adults
    Flanagan EP, Geschwind MD, Lopez-Chiriboga AS, Blackburn KM, Turaga S, Binks S, Zitser J, Gelfand JM, Day GS, Dunham SR, Rodenbeck SJ, Clardy SL, Solomon AJ, Pittock SJ, McKeon A, Dubey D, Zekeridou A, Toledano M, Turner LE, Vernino S, Irani SR JAMA neurology 2023 Jan 80 30-39
    Clinical Reasoning: A 59-Year-Old Man with Thymoma and Constitutional Symptoms, Seizures, and Multifocal CNS Lesions
    Stopschinski BE, Fredrich S, Vernino S, Phillips L, Blackburn KM Neurology 2022 Dec 99 1115-1121
  • Honors & Awards
    • President
      American Autonomic Society (2020-2022)
    • Fellow
      American Autonomic Society (2018)
    • University of Texas Regents Outstanding Teacher Award
      (2016)
    • UT Southwestern Academy of Teachers
      (2014)
    • Program Director Recognition Award
      American Academy of Neurology (CNPD) (2013)
    • Best Doctors
      D Magazine (2012-2023)
    • Fellow
      American Academy of Neurology (2007)
    • Fellow
      American Neurological Association (2005)
    • Founders Award for Clinical Research
      American Academy of Neurology (1998)
    • Woltman Award for Clinical Neurology
      Mayo Clinic (1998)
    • DeBakey Scholar Award
      Baylor College of Medicine (1994)
    • Rush Record Excellence in Neuroscience Award
      Baylor College of Medicine (1992)
  • Professional Associations/Affiliations
    • American Academy of Neurology
    • American Autonomic Society
    • Dysautonomia International (2014)
    • Multiple System Atrophy (MSA) Coalition (2013)