Bret Evers, M.D., Ph.D.
Assistant Professor
School Medical School
Department Pathology | Ophthalmology
Graduate Programs Genetics, Development and Disease, Neuroscience
Education
- Fellowship
- UT Southwestern Medical Center 2017, Ophthalmic Pathology
- Fellowship
- UT Southwestern Medical Center 2017, Ophthalmic Pathology
- Other Post Graduate Training
- UT Southwestern Medical School (2012)
- Medical School
- UT Southwestern Medical Center (2012)
- Graduate School
- UT Southwestern Medical School (2012), Medical Scientist Training Program
- Residency
- UT Southwestern Medical Center (2014), Anatomic Pathology
- Fellowship
- UT Southwestern Medical Center (2016), Neuropathology
Research Interest
- Alzheimer disease
- Analysis of mouse phenotypes
- Comparative histopathology
- Frontotemporal lobar degeneration (FTLD)
- Lipid biology and lipidomics
- Medical and graduate student education
- Neurodegeneration
- Neuropathology
- Ophthalmic pathology
Publications
Featured Publications
- Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.
- Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, Matchett B, Karydas AM, Hsiung GR, Seelaar H, Mol MO, Finger EC, Graff C, Öijerstedt L, Neumann M, Heutink P, Synofzik M, Wilke C, Prudlo J, Rizzu P, Simon-Sanchez J, Edbauer D, Roeber S, Diehl-Schmid J, Evers BM, King A, Mesulam MM, Weintraub S, Geula C, Bieniek KF, Petrucelli L, Ahern GL, Reiman EM, Woodruff BK, Caselli RJ, Huey ED, Farlow MR, Grafman J, Mead S, Grinberg LT, Spina S, Grossman M, Irwin DJ, Lee EB, Suh E, Snowden J, Mann D, Ertekin-Taner N, Uitti RJ, Wszolek ZK, Josephs KA, Parisi JE, Knopman DS, Petersen RC, Hodges JR, Piguet O, Geier EG, Yokoyama JS, Rissman RA, Rogaeva E, Keith J, Zinman L, Tartaglia MC, Cairns NJ, Cruchaga C, Ghetti B, Kofler J, Lopez OL, Beach TG, Arzberger T, Herms J, Honig LS, Vonsattel JP, Halliday GM, Kwok JB, White CL, Gearing M, Glass J, Rollinson S, Pickering-Brown S, Rohrer JD, Trojanowski JQ, Van Deerlin V, Bigio EH, Troakes C, Al-Sarraj S, Asmann Y, Miller BL, Graff-Radford NR, Boeve BF, Seeley WW, Mackenzie IRA, van Swieten JC, Dickson DW, Biernacka JM, Rademakers R Acta Neuropathol. 2019 Feb
- Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.
- Pottier C, Zhou X, Perkerson RB, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, Sánchez-Valle R, Antonell A, Lladó A, Parsons TM, Finch NA, Finger EC, Lippa CF, Huey ED, Neumann M, Heutink P, Synofzik M, Wilke C, Rissman RA, Slawek J, Sitek E, Johannsen P, Nielsen JE, Ren Y, van Blitterswijk M, DeJesus-Hernandez M, Christopher E, Murray ME, Bieniek KF, Evers BM, Ferrari C, Rollinson S, Richardson A, Scarpini E, Fumagalli GG, Padovani A, Hardy J, Momeni P, Ferrari R, Frangipane F, Maletta R, Anfossi M, Gallo M, Petrucelli L, Suh E, Lopez OL, Wong TH, van Rooij JGJ, Seelaar H, Mead S, Caselli RJ, Reiman EM, Noel Sabbagh M, Kjolby M, Nykjaer A, Karydas AM, Boxer AL, Grinberg LT, Grafman J, Spina S, Oblak A, Mesulam MM, Weintraub S, Geula C, Hodges JR, Piguet O, Brooks WS, Irwin DJ, Trojanowski JQ, Lee EB, Josephs KA, Parisi JE, Ertekin-Taner N, Knopman DS, Nacmias B, Piaceri I, Bagnoli S, Sorbi S, Gearing M, Glass J, Beach TG, Black SE, Masellis M, Rogaeva E, Vonsattel JP, Honig LS, Kofler J, Bruni AC, Snowden J, Mann D, Pickering-Brown S, Diehl-Schmid J, Winkelmann J, Galimberti D, Graff C, Öijerstedt L, Troakes C, Al-Sarraj S, Cruchaga C, Cairns NJ, Rohrer JD, Halliday GM, Kwok JB, van Swieten JC, White CL, Ghetti B, Murell JR, Mackenzie IRA, Hsiung GR, Borroni B, Rossi G, Tagliavini F, Wszolek ZK, Petersen RC, Bigio EH, Grossman M, Van Deerlin VM, Seeley WW, Miller BL, Graff-Radford NR, Boeve BF, Dickson DW, Biernacka JM, Rademakers R Lancet Neurol 2018 Jun 17 6 548-558
- Lipidomic and Transcriptomic Basis of Lysosomal Dysfunction in Progranulin Deficiency.
- Evers BM, Rodriguez-Navas C, Tesla RJ, Prange-Kiel J, Wasser CR, Yoo KS, McDonald J, Cenik B, Ravenscroft TA, Plattner F, Rademakers R, Yu G, White CL, Herz J Cell Rep 2017 Sep 20 11 2565-2574
- Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin.
- Evers BM, Farooqi MS, Shelton JM, Richardson JA, Goldstein JL, Brown MS, Liang G J. Invest. Dermatol. 2010 May 130 5 1237-48
- Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin.
- Engelking LJ, Evers BM, Richardson JA, Goldstein JL, Brown MS, Liang G J. Clin. Invest. 2006 Sep 116 9 2356-65
- Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.
- Engelking LJ, Liang G, Hammer RE, Takaishi K, Kuriyama H, Evers BM, Li WP, Horton JD, Goldstein JL, Brown MS J. Clin. Invest. 2005 Sep 115 9 2489-98
- Myofiber-type-dependent 'boulder' or 'multitudinous pebble' formations across distinct amylopectinoses.
- Mitra S, Chen B, Shelton JM, Nitschke S, Wu J, Covington L, Dear M, Lynn T, Verma M, Nitschke F, Fuseya Y, Iwai K, Evers BM, Minassian BA, Acta Neuropathol 2024 Feb 147 1 46
- Association of genetic variation in COL11A1 with adolescent idiopathic scoliosis.
- Yu H, Khanshour AM, Ushiki A, Otomo N, Koike Y, Einarsdottir E, Fan Y, Antunes L, Kidane YH, Cornelia R, Sheng RR, Zhang Y, Pei J, Grishin NV, Evers BM, Cheung JPY, Herring JA, Terao C, Song YQ, Gurnett CA, Gerdhem P, Ikegawa S, Rios JJ, Ahituv N, Wise CA, Elife 2024 Jan 12
- Intermittent alternating magnetic fields diminish metal-associated biofilm in vivo.
- Shaikh S, Lapin NA, Prasad B, Sturge CR, Pybus C, Pifer R, Wang Q, Evers BM, Chopra R, Greenberg DE, Sci Rep 2023 Dec 13 1 22456
- Tau seeding without tauopathy.
- LaCroix MS, Artikis E, Hitt BD, Beaver JD, Estill-Terpack SJ, Gleason K, Tamminga CA, Evers BM, White CL, Caughey B, Diamond MI, J Biol Chem 2023 Dec 105545
Books
Featured Books
Mass effect and edema. In Neuropathologic and Neuroradiologic Correlations: A differential diagnostic text and atlas
Evers, B., Danielsen, T., and Kumar, M. (2017). Cambridge, UK, Cambridge University Press
Honors & Awards
- Carl B. and Florence E. King Foundation Endowed Fund in Alzheimers Disease Research Award
(2015-2017) - Vernie A. Stembridge, M.D., Scholarship Award in Pathology (UT Southwestern)
(2012) - Distinguished Biochemistry Research Scholar (Texas A&M University)
(2004) - Barry M. Goldwater Scholar
(2002) - Bruce D. Fallis, M.D., Resident Award for Teaching (UT Southwestern)
2013 and 2014 - Commencement Marshal for the Medical School Classes of 2022 and 2023
- Outstanding Teacher Award (UT Southwestern Medical School)
2017, 2018, 2019, 2020, 2021, and 2022 - UT Southwestern Academy of Teachers (SWAT) Outstanding Biomedical Science Educator
2018 and 2022
Professional Associations/Affiliations
- American Association of Neuropathologists (2014)
- Phi Beta Kappa (2004)
- Sigma Xi (2004)
- Verhoeff-Zimmerman Society (2019)