Featured Publications
Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR
Michaely P., Zhao Z., Li W.P., Garuti R., Huang L.J., Hobbs H.H., Cohen J.C. EMBO Journal July 2007 26(14) 3273-82
The Membrane Proximal Region Of The Thrombopoietin Receptor (TpoR) Confers Its High Surface Expression by JAK2-dependent and independent mechanisms
Tong W, Sulahian R, Gross AW, Hendon N, Lodish HF, and Huang L.J. Journal of Biological Chemistry December 2006 281(50) 38930-40
Amino acid residues 268-276 of the erythropoietin receptor contain an endocytosis motif and are required for erythropoietin-mediated proliferation via the receptor.
Flint-Ashtamker G., Eisen-Lev R., Cohen J., Huang L.J., and Newmann D. 2002 April 2002 FEBS Letters 518 (1-3) 189-94
The N-terminal domain of Janus Kinase 2 is required for Golgi processing and cell surface expression of erythropoietin receptor.
Huang L.J., Constantinescu N. S., and Lodish H. F. Molecular Cell December 2001 8 1327-1338
The Erythropoietic receptor cytosolic juxtamembrane domain contains an essential, precisely oriented, hydrophobic motif.
Constantinescu N. S., Huang L.J., Nam H. S., and Lodish H. F. Molecular Cell February 2001 7 377-385