2003 University of California-San Francisco. PhD, biochemistry and biophysics. Advisor: Jonathan S. Weissman

1998 Harvard University, Cambridge, MA. AB and AM, chemistry. Advisor: James C. Wang

1994 State College Area High School, State College, PA



2004-2006 UT Southwestern, Postdoctoral Fellow. Advisor: Steven L. McKnight



2007-present Assistant Professor, Department of Biochemistry, UT Southwestern



Graduate School Harvard University , Chemistry
Graduate School University of California-San Francisco (2003)

Research Interest

  • Bioinformatic analysis of temporal gene expression and metabolite profiling data
  • Cell growth control
  • Mechanisms by which cellular processes are coupled to metabolic state
  • Metabolic cycles
  • Oxidative stress, nutritional stress


Featured Publications LegendFeatured Publications

Restriction of DNA replication to the reductive phase of the metabolic cycle protects genome integrity
Chen, Z., Odstrcil, E.A., Tu, B.P., McKnight, S.L. Science June 2007 316 1916-1919
High-resolution timing of cell cycle-regulated gene expression
Rowicka, M., Kudlicki, A., Tu, B.P., Otwinowski, Z. Proc Natl Acad Sci USA 2007
Metabolic cycles as an underlying basis of biological oscillations
Tu, B.P., McKnight, S.L. Nat Rev Mol Cell Biol. September 2006 7 696-701
Oxidative protein folding in eukaryotes: mechanisms and consequences
Tu, B.P., Weissman, J.S. J Cell Biol. February 2004 164 341-346
The FAD- and O(2)-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum
Tu, B.P., Weissman, J.S. Molecular Cell November 2002 10 983-994

Honors & Awards

  • Damon Runyon-Rachleff Innovation Award
  • Packard Fellowship
  • W. W. Caruth, Jr. Scholar in Biomedical Research
  • Burroughs Wellcome Fund
    Career Award in Biomedical Sciences (2006)
  • AAAS & GE Healthcare
    Young Scientist Award Regional Winner - North America (2004)
  • Helen Hay Whitney Foundation
    Postdoctoral Fellowship (2004)