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Dr. Joshua Koch is interested in better understanding acquired brain injury and how improved care in the intensive care unit can prevent it. He serves as the site primary investigator for the multi-center trial, Therapeutic Hypothermia after Pediatric Cardiac Arrest (THAPCA). This trial is funded by the National Heart, Lung, and Blood Institute, and began enrollment on September 1, 2009.

His other research efforts focus on optimizing the post-operative management of patients with congenital heart disease. He is the primary investigator for a study looking at the use of tolvaptan in pediatric patients with hyponatremia and heart failure. He is a co-investigator on the CHANGE study (Congenital Heart and Adrenal Gland Examination) and a study on appropriate dosing of amlodipine in single ventricle patients.

Josh serves as the Clinical Director of Critical Care Services at Children’s Medical Center and is interested in quality improvement as it relates to efficient health care systems. He is the site medical director for both VPS (Virtual PICU Systems) and PC4 (Pediatric Cardiac Critical Care Consortium) and is currently engaged in quality improvement projects designed to improve identification and optimization of care of the deteriorating cardiac patient, catheter associated urinary tract infections, and health care acquired pressure ulcers.


Medical School
University of Kansas School of Medicine (2001)
UT Southwestern/Children's Medical Center (2002), Pediatrics
UT Southwestern/Children's Medical Center (2004), Pediatrics
UT Southwestern/Children's Medical Center (2005), Pediatrics
UT Southwestern/Children's Medical Center (2008), Pediatric Critical Care Medicine

Specialty Areas

Clinical Interest

  • Neurocritical Care
  • Research Interest

    • Adrenal function in children with congenital heart disease
    • Neurologic outcomes in children with congenital heart disease
    • Team dynamics in the intensive care unit setting


    Featured Publications LegendFeatured Publications

    Elevated cranial ultrasound resistive indices are associated with improved neurodevelopmental outcomes one year after pediatric cardiac surgery: A single center pilot study.
    Jenks CL, Hernandez A, Stavinoha PL, Morris MC, Tian F, Liu H, Garg P, Forbess JM, Koch J Heart Lung 2017 May
    Pediatric cardiac arrest due to drowning and other respiratory etiologies: Neurobehavioral outcomes in initially comatose children.
    Slomine BS, Nadkarni VM, Christensen JR, Silverstein FS, Telford R, Topjian A, Koch JD, Sweney J, Fink EL, Mathur M, Holubkov R, Dean JM, Moler FW Resuscitation 2017 Mar
    Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children.
    Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC, Clark AE, Dean JM N. Engl. J. Med. 2017 01 376 4 318-329
    Use of nesiritide in critically ill children with biventricular dysfunction suffering from oliguria despite standard heart-failure management.
    Das BB, Koch J, Dimas V, Guleserian K, Nugent A Cardiol Young 2015 Dec 1-5
    Feasibility Study Evaluating Therapeutic Hypothermia for Refractory Status Epilepticus in Children.
    Buttram SD, Au AK, Koch J, Lidsky K, McBain K, O'Brien N, Zielinski BA, Bell MJ Ther Hypothermia Temp Manag 2015 Dec 5 4 198-202
    The association of congenital heart disease with necrotizing enterocolitis in preterm infants: a birth cohort study.
    Motta C, Scott W, Mahony L, Koch J, Wyckoff M, Reisch J, Burchfield PJ, Brion LP J Perinatol 2015 Aug
    Therapeutic Hypothermia after Out-of-Hospital Cardiac Arrest in Children.
    Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Clark AE, Browning B, Pemberton VL, Page K, Shankaran S, Hutchison JS, Newth CJ, Bennett KS, Berger JT, Topjian A, Pineda JA, Koch JD, Schleien CL, Dalton HJ, Ofori-Amanfo G, Goodman DM, Fink EL, McQuillen P, Zimmerman JJ, Thomas NJ, van der Jagt EW, Porter MB, Meyer MT, Harrison R, Pham N, Schwarz AJ, Nowak JE, Alten J, Wheeler DS, Bhalala US, Lidsky K, Lloyd E, Mathur M, Shah S, Wu T, Theodorou AA, Sanders RC, Dean JM N. Engl. J. Med. 2015 Apr
    Tolvaptan Increases Serum Sodium in Pediatric Patients With Heart Failure.
    Regen RB, Gonzalez A, Zawodniak K, Leonard D, Quigley R, Barnes AP, Koch JD Pediatr Cardiol 2013 Mar

    Honors & Awards

    • Best Doctors in Dallas
      D Magazine (2015-2016)
    • Southern Society Pediatric Research
      Clinical Young Investigator Award (2005)
    • Resident Award for Pediatric Research
    • D. Cramer Reed Award
      Excellence in Public Health (2001)
    • Guthrie Excellence in Pediatrics Award

    Professional Associations/Affiliations

    • Pediatric Cardiac Intensive Care Society (2009)
    • Dallas County Medical Society (2003-2006)
    • American Academy of Pediatrics (2001-2005)
    • Mortar Board National Honor Society