Featured Publications
The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine.
Vaishnava S, Yamamoto M, Severson KM, Ruhn KA, Yu X, Koren O, Ley R, Wakeland EK, Hooper LV Science 2011 Oct 334 6053 255-8
Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface.
Ismail AS, Severson KM, Vaishnava S, Behrendt CL, Yu X, Benjamin JL, Ruhn KA, Hou B, DeFranco AL, Yarovinsky F, Hooper LV Proc. Natl. Acad. Sci. U.S.A. 2011 May 108 21 8743-8
Molecular basis for peptidoglycan recognition by a bactericidal lectin.
Lehotzky RE, Partch CL, Mukherjee S, Cash HL, Goldman WE, Gardner KH, Hooper LV Proc. Natl. Acad. Sci. U.S.A. 2010 Apr 107 17 7722-7
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface.
Vaishnava S, Behrendt CL, Ismail AS, Eckmann L, Hooper LV Proc. Natl. Acad. Sci. U.S.A. 2008 Dec 105 52 20858-63
Symbiotic bacteria direct expression of an intestinal bactericidal lectin.
Cash HL, Whitham CV, Behrendt CL, Hooper LV Science 2006 Aug 313 5790 1126-30
Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity.
Du Y, Yang M, Lee S, Behrendt CL, Hooper LV, Saghatelian A, Wan Y Genes Dev. 2012 Jun 26 12 1306-11
Interactions between the microbiota and the immune system.
Hooper LV, Littman DR, Macpherson AJ Science 2012 Jun 336 6086 1268-73
Epithelial antimicrobial defence of the skin and intestine.
Gallo RL, Hooper LV Nat. Rev. Immunol. 2012 12 7 503-16
You AhR What You Eat: Linking Diet and Immunity.
Hooper LV Cell 2011 Oct 147 3 489-91
Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis.
Li XD, Chiu YH, Ismail AS, Behrendt CL, Wight-Carter M, Hooper LV, Chen ZJ Proc. Natl. Acad. Sci. U.S.A. 2011 Oct 108 42 17390-5
