I was born in Fayetteville, NC and grew up outside of Philadelphia, PA. As an undergraduate at the University of North Carolina I worked in the laboratories of Paul Kropp and, at the National Institutes of Environmental Health Sciences, Masahiko Negishi. I completed my graduate studies at Harvard University in 2001 under the direction of Eric Jacobsen, studying epoxide ring opening reactions. I then moved to Yale University for a postdoc with John Wood where I focused on total synthesis. I joined the faculty at UT Southwestern in 2003, and my research group currently focuses on natural products synthesis, medicinal chemistry and synthetic methodology.

Lab website:


Undergraduate University of North Carolina at Chapel Hill (1996), Chemistry
Graduate School Harvard University (2001), Chemistry

Research Interest

  • Discovery and application of new chemical reactions; synthesis of biologically active small molecules


Featured Publications LegendFeatured Publications

Development of Proneurogenic, Neuroprotective Small Molecules

MacMillan, K.S.; McKnight, S.L.; Pieper, A.A.; De Brabander, J. K.; Ready, J.M. J. Am. Chem. Soc. 2011 133 1428-1437

Titanium-Mediated Oxidative Arylation of Homoallylic Alcohols

Lee, K.S.; Ready, J.M. Angew. Chem. Int. Ed. 2011 50 2111-2114

Allenes in Asymmetric Catalysis: Asymmetric Ring Opening of meso-Epoxides Catalyzed by Allene-Containing Phosphine Oxides

Pu, X.; Qi, X.; Ready, J. M J. Am. Chem. Soc. 2009 131 10364-10365

Direct and Stereospecific Synthesis of Allenes via Reduction of Propargylic Alcohols with Cp2Zr(H)Cl

Pu, X.; Ready, J. M. J. Am. Chem. Soc. 2008 130 10874-10875

Preparation of Substituted Enol Derivatives from Terminal Alkynes and thier Synthetic Utility

Debergh, J. R.; Spivey, K. M.; Ready, J. M. J. Am. Chem. Soc. 2008 130 7828-7829

Honors & Awards

  • Alfred P. Sloan Foundation Fellow
  • Amgen Young Investigator Award
  • NSF CAREER Award
  • Southwestern Medical Center Scholar in Biomedical Research
  • NIH Postdoctoral Fellowhsip