Education

Undergraduate
Unlisted - International Colle (1993), Biochemistry
Graduate School
Unlisted - International Colle (1996), Biochemistry
Graduate School
University of Tokyo (2003), Agriculture

Research Interest

  • Atophic dermatitis
  • Langerhans and dendritic cells

Publications

Featured Publications LegendFeatured Publications

Inhibition of T-cell Activation by Syndecan-4 Is Mediated by CD148 Through Protein Tyrosine Phosphatase Activity.
Chung, JS., Ponciano D. Cruz Jr, and K. Ariizumi Eup. J. Immunol. 2011 41 1794-1799
DC-HIL/Gpnmb promotes growth of melanoma in mice by inhibiting the activation of tumor-reactive T cells.
*Tomihari M., *JS. Chung, H. Akioshi, Ponciano D. Cruz Jr., and K. Ariizumi * equal contribution Cancer Res. 2010 70 5778-5787
Depleting syndecan-4+ T lymphocytes using toxin-bearing DC-HIL: A new opportunity for treating activated T cell-driven disease.
*Akiyoshi H., *JS. Chung, M. Tomihari, Ponciano D. Cruz Jr., and K. Ariizumi * equal contribution. J. Immunol. 2010 184 3554-3561
The DC-HIL/syndecan-4 pathway inhibits human allogeneic T cell response.
Chung, JS, M. Bonkobra, M. Tomihari, Ponciano D. Cruz Jr., and K. Ariizumi Eup. J. Immunol. 2009 39 965-974
Binding of dermatophytic fungi induces tyrosine phoshorylation and potentiates antigen presenting cell function.
Chung, JS, T. Yudate, M. Tomihari, H. Akiyoshi, Ponciano D. Cruz Jr., and K. Ariizumi J. Immunol. 2009 183 5190-5198
Gpnmb is a melanosome-associated glycoprotein that contributes to melanocytes/keratinocyte adhesion in a RGD-dependent fashion.
Tomihari, M., SH. Hwang, JS. Chung, Ponciano D. Cruz Jr., and K. Ariizumi Exp. Dermatol. 2009 18 586-595
Syndecan-4 mediates the coinhibitory function of DC-HIL on T cell activation.
Chung JS, Dougherty I, Cruz PD, and K. Ariizumi J. Immunol. 2007 179 5778-5784
Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor  chain to induce innate immune responses.
Kota, S., XI. Yang, T. Yudate, JS. Chung, J. Wu, K. Luby-Phelps, R. P. Kimberly, D. Underhill, P. D. Cruz, Jr., and K. Ariizumi J. Biol. Chem. 2006 281 38854-38866

Honors & Awards

  • Albert M. Kligman Fellowship
    Society for Investigative Dermatology (2005)
  • Fellowship
    Japan Society for Bioscience, Biotechnology, and Agrochemistry (2002)

Professional Associations/Affiliations

  • Japan Society for Bioscience, Biotechnology, and Agrochemistry
  • Society for Investigative Dermatology