Featured Publications
Olig2 Targets Chromatin Remodelers To Enhancers To Initiate Oligodendrocyte Differentiation
Yu Y., Y. Chen, B. Kim, H. Wang, C. Zhao, X. He, L. Liu, W. Liu, L. M. N. Wu, M. Mao, J. R. Chan, J. Wu and Q. R. Lu Cell 2013 152 1-14
Dual-mode Modulation of Smad Signaling by Smad-interacting Protein Sip1 is Required for Myelination in the CNS
Weng, Q., Y. Chen1, H. Wang, X. Xu, B. Yang, Q. He, W. Shou, Y. Chen, Y. Higashi, V. van den Berghe, E. Seuntjens, S. Kernie, P. Bukshpun, E. Sherr, D. Huylebroeck, Lu Q.R. Neuron 2012 73
HDAC-mediated Deacetylation of NF-κB is Critical for Schwann cell Myelination
Ying Chen, Haibo Wang, Sung Ok Yoon, Xiaomei Xu, Michael Hottiger, Haesun Kim, Eric N. Olson, and Q. Richard Lu Nature Neuroscience April 2011 2011 Apr;14(4):437-41.
MicroRNA-mediated control of oligodendrocyte differentiation
Zhao, X., He, X., Han, X., Yu, Y., Ye, F., Chen, Y., Hoang, T., Xu, X., Mi, Q.S., Xin, M., Wang, F., Appel, B. and Lu, Q.R. Neuron March 2010 65 612-626
HDAC1 and HDAC2 Regulate Oligodendrocyte Differentiation By Disrupting β-Catenin-TCF Interaction
Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR Nature Neuroscience July 2009 v12 829-838
The oligodendrocyte-specific G-protein coupled receptor GPR17 is a cell intrinsic timer of myelination
Chen, Y. H. Wu, S. Wang, H. Koito, J. Li, J. Hoang, F. Ye, S. S. Escobar, A. Gow, H. A. Arnett, B. D. Trapp, N. J. Karandikar, J. Hsieh and Q. R. Lu Nature Neuroscience 2009 12 1398-1406
Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.
Lu, Q.R., Sun, T., Zhu, Z., Ma, N., Garcia, M., Stiles, C.D. and Rowitch, D. Cell 2002 109 75-86
Sonic Hedgehog-Regulated Oligodendrocyte Lineage Genes Encoding bHLH Proteins in the Mammalian Central Nervous System.
Lu, Q.R., Yuk, D., Alberta, J.A., Zhu, Z., Pawlitzky, I., Chan, J., McMahon, A. P., Stiles, C. D. and Rowitch, D. H. NEURON 2000 25 317-329
