Improving the Design of a MscL-Based Triggered Nanovalve.
Iscla I, Eaton C, Parker J, Wray R, Kovács Z, Blount P Biosens Bioelectron 2013 3 1 171-184
The dynamics of protein-protein interactions between domains of MscL at the cytoplasmic-lipid interface.
Iscla I, Wray R, Blount P Channels (Austin) 2012 Jul-Aug 6 4 255-61
Sensing and Responding to Membrane Tension: The Bacterial MscL Channel as a Model System.
Iscla I, Blount P Biophys. J. 2012 Jul 103 2 169-74
The oligomeric state of the truncated mechanosensitive channel of large conductance shows no variance in vivo.
Iscla I, Wray R, Blount P Protein science : a publication of the Protein Society 2011 Jul 1638-42
An in vivo screen reveals protein-lipid interactions crucial for gating a mechanosensitive channel.
Iscla I, Wray R, Blount P FASEB J. 2011 Feb 25 2 694-702
On the structure of the N-terminal domain of the MscL channel: helical bundle or membrane interface.
Iscla I, Wray R, Blount P Biophys. J. 2008 Sep 95 5 2283-91
Disulfide trapping the mechanosensitive channel MscL into a gating-transition state.
Iscla I, Levin G, Wray R, Blount P Biophys. J. 2007 Feb 92 4 1224-32
Defining the physical gate of a mechanosensitive channel, MscL, by engineering metal-binding sites.
Iscla I, Levin G, Wray R, Reynolds R, Blount P Biophys. J. 2004 Nov 87 5 3172-80
Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance.
Zhang X, Wang J, Feng Y, Ge J, Li W, Sun W, Iscla I, Yu J, Blount P, Li Y, Yang M Proc. Natl. Acad. Sci. U.S.A. 2012 Oct 109 44 18180-5
Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel.
Edwards MD, Li Y, Kim S, Miller S, Bartlett W, Black S, Dennison S, Iscla I, Blount P, Bowie JU, Booth IR Nat. Struct. Mol. Biol. 2005 Feb 12 2 113-9