Phosphorylation of the human micro-RNA generating complex mediates MAPK/Erk signaling
Z. Paroo, X. Ye, S. Chen, and Q. Liu Cell October 2009 139 112-122
C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation
Y. Liu, X. Ye, F. Jiang, C. Liang, D. Chen, P. Jun, L.N. Kinch, N.V. Grishin, Q. Liu Science August 2009 325 750-753
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway.
Q. Liu, T. A. Rand, S. Kalidas, F. Du, H. Kim, D.P. Smith, X. Wang Science 2003 301 1921-1925
Chk1 is an essential kinase that is regulated by Atr and required for the G2/M DNA damage checkpoint.
Q. Liu, S. Guntuku, X. Cui, S. Matsuoka, D. Cortez, K. Tamai, G. Luo, S. Carattini-Rivera, F. Demayo, A. Bradley, L.A. Donehower, and S.J. Elledge Genes Dev. 2000 14 1448-1459
The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes.
Q. Liu, M. Z. Li, D. Liebham, D. Cortez, S. J. Elledge Curr. Biol. 1998 8 1300-1309
Sjogren Syndrome Antigen B (SSB)/La promotes global microRNA expression by binding microRNA precursors through stem-loop recognition.
C. Liang, K. Xiong, K.E. Szulwuch, Y. Zhang, Z. Wang, J. Peng, M. Fu, P. Jing, H.I. Suzuki, Q. Liu. J Biol Chem 2013 288 723-36
Autoantigen La promotes RNAi, antiviral response, and transposon silencing by facilitating multi-turnover RISC catalysis.
Y. Liu, H. Tan, H. Tian, C. Liang, S. Chen, Q. Liu. Mol. Cell 2011 44: 502-508
Structure of C3PO and mechanism of human RISC activation.
X. Ye, N. Huang, Y. Liu, Z. Paroo, C. Huerta, P. Li, S. Chen, Q. Liu*, H. Zhang* (co-corresponding authors) Nat Struct Mol Biol. 2011 18: 650-657
The functional anatomy of Drosophiila microRNA-generating enzyme
X. Ye, P. Zain, and Q. Liu J. Biol. Chem. July 2007 282 (39) 28373-28378
The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells.
J. Park*, X. Liu*, T. Strauss, D. McKearin, and Q. Liu Curr. Biol. 2007 17 533-538