Binu Thomas, Ph.D. Assistant Professor School Medical School Department Advanced Imaging Research Center | Peter O'Donnell Jr. Brain Institute | Radiology Graduate Programs Biomedical Engineering Biography Dr. Thomas is an Assistant Professor at the Advanced Imaging Research Center, Department of Biomedical Engineering, and the Department of Radiology at UT Southwestern. He also has an adjunct appointment at the Department of Bioengineering at UT Arlington and the Department of Biomedical Engineering at UT Dallas. He received his bachelor's from Mumbai University and master's and PhD degrees in Biomedical Engineering from UT Southwestern jointly with UT Arlington. His PhD research was focused on technical developments in cerebrovascular reactivity to carbon-dioxide in humans and its applications to assess changes in aging and mild cognitive impairment. His post-doctoral research at UT Dallas was in neuroscience and neuroimaging. As Assistant Professor at UT Southwestern, he has broadened his research to understand brain vascular function, metabolism and physiology in aging, mild cognitive impairment, hypertension, obesity and its comorbidities as it relates to dementia risk. Education Graduate School University of Texas at Arlingt (2002), Biomedical Engineering Research Interest Aging Cerebral blood flow Cerebral metabolic rate of oxygen consumption Cerebrovascular physiology Mild cognitive impairment and Alzheimer's disease Publications Featured Publications Cognition and brain oxygen metabolism improves after bariatric surgery-induced weight loss: A pilot study. Anwar N, Tucker WJ, Puzziferri N, Samuel TJ, Zaha VG, Lingvay I, Almandoz J, Wang J, Gonzales EA, Brothers RM, Nelson MD, Thomas BP, Front Endocrinol (Lausanne) 2022 13 954127 Hippocampal and Rostral Anterior Cingulate Blood Flow is Associated with Affective Symptoms in Chronic Traumatic Brain Injury. Thomas BP, Tarumi T, Wang C, Zhu DC, Tomoto T, Munro Cullum C, Dieppa M, Diaz-Arrastia R, Bell K, Madden C, Zhang R, Ding K, Brain Res 2021 Aug 147631 Brain Perfusion Change in Patients with Mild Cognitive Impairment After 12 Months of Aerobic Exercise Training. Thomas BP, Tarumi T, Sheng M, Tseng B, Womack KB, Cullum CM, Rypma B, Zhang R, Lu H, J. Alzheimers Dis. 2020 75 2 617-631 Reduced global brain metabolism but maintained vascular function in amnestic mild cognitive impairment. Thomas BP, Sheng M, Tseng BY, Tarumi T, Martin-Cook K, Womack KB, Cullum MC, Levine BD, Zhang R, Lu H, J. Cereb. Blood Flow Metab. 2017 Apr 37 4 1508-1516 Cerebrovascular reactivity in the brain white matter: magnitude, temporal characteristics, and age effects. Thomas BP, Liu P, Park DC, van Osch MJ, Lu H, J. Cereb. Blood Flow Metab. 2014 Feb 34 2 242-7 Physiologic underpinnings of negative BOLD cerebrovascular reactivity in brain ventricles. Thomas BP, Liu P, Aslan S, King KS, van Osch MJ, Lu H, Neuroimage 2013 Dec 83 505-12 Life-long aerobic exercise preserved baseline cerebral blood flow but reduced vascular reactivity to CO2. Thomas BP, Yezhuvath US, Tseng BY, Liu P, Levine BD, Zhang R, Lu H, J Magn Reson Imaging 2013 Nov 38 5 1177-83 Associations Between High-Density Lipoprotein Cholesterol Efflux and Brain Grey Matter Volume. Giacona JM, Wang J, Zhang R, Kelley BJ, Hajjar I, Thomas BP, Yu FF, de Lemos JA, Rohatgi A, Vongpatanasin W, J Clin Med 2024 Oct 13 20 Functional activation of pyruvate dehydrogenase in human brain using hyperpolarized [1-13 C]pyruvate. Zaidi M, Ma J, Thomas BP, Peña S, Harrison CE, Chen J, Lin SH, Derner KA, Baxter JD, Liticker J, Malloy CR, Bartnik-Olson B, Park JM, Magn Reson Med 2024 Jan Deep-learning-enabled brain hemodynamic mapping using resting-state fMRI. Hou X, Guo P, Wang P, Liu P, Lin DDM, Fan H, Li Y, Wei Z, Lin Z, Jiang D, Jin J, Kelly C, Pillai JJ, Huang J, Pinho MC, Thomas BP, Welch BG, Park DC, Patel VM, Hillis AE, Lu H, NPJ Digit Med 2023 Jun 6 1 116 Results 1-10 of 38 1 2 3 4 Next Last Books Featured Books Cerebrovascular Reactivity (CVR) in Aging, Cognitive Impairment, and Dementia. In Cerebrovascular Reactivity Hanzhang Lu, Binu P Thomas, Peiying Liu (2022). New York, NY, Humana Professional Associations/Affiliations International Society for Magnetic Resonance in Medicine (ISMRM) (2010) Peter O'Donnell Jr. Brain Institute (2022)
