Amelia Eisch, Ph.D.

Associate Professor

Department: Psychiatry

Graduate Programs: Integrative Biology, Neuroscience

Biography

Cell birth and cell death - why are new cells born in the adult brain, and how do these new cells influence plasticity? How do adult-generated cells impact the development of psychiatric disorders like addiction, depression, and PTSD? The best place to learn more about these questions and about the Eisch Lab and its key members. Please visit our lab web site.

Education

Undergraduate Yale University (1990)
Graduate School University of California-Irvine (1997)

Research Interests

  • Inability of the brain to "adapt" may contribute to - or exacerbate - myriad psychiatric disorders.
  • Keywords: motivated behaviors, adult neurogenesis, hippocampus, neuroplasticity, addiction, morphine, cocaine, depression, PTSD, dementia, cell cycle regulation, BrdU, inducible transgenic mice, viral-mediated gene transfer, confocal microscopy, immunohistochemistry, behavioral analysis
  • My research focuses on the role that mediators of developmental neuroplasticity play in adult neuroplasticity, particularly neuroplasticity that contribute to normal motivated behaviors as well as psychiatric disorders.
  • The main mediators of neuroplasticity we study are new neurons in the adult brain, or adult neurogenesis. The motivated behaviors we assess have relevance to addiction, depression, PTSD, as well as general aspects of learning and memory.
  • To this extent, we aim to understand "what is adult neurogenesis good for?" as well as "what is good for adult neurogenesis?" For more on my laboratory's research, please visit the Eisch Lab Website at www3.utsouthwestern.edu/eisch/

Publications

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Honors/Awards

  • Inaugural Seymour Benzer Lecturer, National Academy of Sciences
    Established by Nobel Laureat Sydney Brenner to honor a researchers in neuroscience or genetics (2011)
  • Kavli Frontiers of Science Fellow, National Academy of Sciences
    Selected as Fellow and Chair of session on Neural Stem Cells (2010)
  • Member of CSR/NIH Standing Study Section on Neurobiology of Motivated Behavior
    Four year term reviewing NIH grants (2009)
  • National Institute on Drug Abuse
    K02 Independent Investigator Award (2008)
  • National Alliance for Research on Schizophrenia and Depression
    Young Investigator Award (2004)
  • National Institute on Drug Abuse
    RO1: Regulation of Adult Neurogenesis by Opiates (2004)
  • Society for Neuroscience
    Minisympoisum on Adult Neurogenesis chosen for presentation at annual meeting (2004)
  • National Alliance for Research on Schizophrenia and Depression
    Young Investigator Award (2002)

Professional Associations/Affiliations

  • Sigma Xi
  • Society for Neuroscience