Deborah Carlson, Ph.D. Assistant Professor School Medical School Department Surgery | Pediatrics Biography Deborah Carlson, Ph.D., has contributed greatly to UT Southwestern, from her first assignment as a research scientist in 2000 to her current post of assistant professor in the pediatrics and surgery departments. She has a Ph.D. from the Department of Cellular and Molecular Biology at State University of New York and completed a post-doctoral fellowship in the Department of Chemistry at the University of Nebraska at Lincoln. Dr. Carlson has investigated cardiac dysfunction and other topics, work that has been sponsored by the National Institutes of Health. She is active in professional organizations, including the American Burn Association and the International Shock Society, with both groups bestowing awards on her for her research. Dr. Carlson is an author of numerous publications, which have recently included articles on heart dysfunction during sepsis and on ways to improve outcomes after burn injury. Education Undergraduate Central South Univ, Xiang-Ya S , None Undergraduate Unlisted - College or Universi , None Graduate School Central South Univ, Xiang-Ya S , None Graduate School Unlisted - College or Universi , None Research Interest Cardiac function following burn injury and sepsis The Role of Matrix Metalloproteinases in Cardiac Dysfunction Publications Featured Publications Burn Trauma Alters Calcium Transporter Protein Expression in the Heart. Ballard-Croft C, Carlson DL, Maas DL, Horton JW J Applied Physiology 2004 97(4) 1470-1476 Endotoxin infusion in mice results in cardiac apotosis via a TNF-a dependent pathway Carlson DL, White DJ, Horton JW and Giroir BP American Journal of Physiology: Heart and Circulatory Physiology 2003 Accepted, 2003. Myocyte apoptosis via endotoxin Carlson DL, LIghtfoot, Jr. E, Bryant DD, Haudek SB, Maass DL and Horton JW American Journal of Physiology: Heart and Circulatory Physiology 2002 282 H1907-H1914 Antioxidant Vitamin Therapy Alters Sepsis-related Apoptotic Myocardial Activity and Inflammatory Responses. Carlson D, Maas DL, Tan J, Horton JW J Physiol Heart Circ Physiol December 2006 291(6) H2779-H2789 Cardiac Molecular Signaling after Burn Trauma Carlson DL, Horton JW J Burn Care Research September 2006 27(5) 669-75 Macrophage Migration Inhibitory Factor (MIF) is a Burn Trauma Induced Cardiac Depressant. Willis MS, Carlson DL, DiMiao JM, White MD, White DJ, Horton JW, Giroir BP. AJP Heart and Circ. 2005 288(2) H795-H804 TNF-alpha Induced Caspase Activation Mediates Endotoxin Related Cardiac Dysfunction. Carlson DL, Willis MS, White DJ, Horton JW, Giroir BP Critical Care Medicine 2005 33(5) 1021-1028 A three-component dicamba O-demethylase from Pseudomonas maltophilia, strain DI-6: purification and characterization. Chakraborty S., Behrens M., Herman PL, Arendsen AF, Hagan WR, Carlson DL, Wang XZ, Weeks DP Arch Biochem Biophys 2005 437(1) 20-28 Results 1-8 of 8 1 Honors & Awards Member since 2005International Shock Society Presential Committee for Publications (2007) Research Citation FinalistSociety for Critical Care Medicine 36th Annual Congress (2007) Most Outstanding Presentation AwardShock Society 28th Annual Conference (2005) Outstanding Young Investigator AwardJames Carrico Research Forum, UT Southwestern Medical Center at Dallas (2001) PresidentNational Biological Honor Society (1989) Professional Associations/Affiliations 2005-2006 International Shock Society Presidential Committee for Publications American Burn Association American Heart Association International Shock Society Society of Critical Care Medicine