Anne Satterthwaite, Ph.D.

Associate Professor

Endowed Title: Peggy Chavellier Professorship for Arthritis Research and Treatment; Southwestern Medical Foundation Scholar in Biomedical Research

Department: Internal Medicine, Immunology

Graduate Programs: Immunology

Biography

Prior to joining the UT Southwestern faculty in 2000, Dr. Anne Satterthwaite received a bachelors degree in Life Sciences from MIT and a PhD in Cell and Developmental Biology from the Division of Medical Sciences at Harvard University. She subsequently pursued postdoctoral work with Dr. Owen Witte at UCLA where she developed an interest in understanding the signaling pathways that regulate B lymphocyte development and function.

Education

Undergraduate Massachusetts Institute of Technology (1987), Science
Graduate School Harvard University (1993), Biology

Research Interests

  • Autoimmunity
  • B cell development
  • Immunodeficiency
  • Signal transduction

Publications

Featured Publications Legend

Featured Publications

Foxo3-/- mice demonstrate reduced numbers of pre-B and recirculating B cells but normal splenic B cell subpopulations.

Hinman RM, Nichols WA, Diaz TM, Gallardo TD, Castriollon DH, and Satterthwaite AB International Immunology July 2009 21 831-842

Btk regulates localization, in vivo activation, and class switching of anti-DNA B cells.

Halcomb KE, Musuka S, Gutierrez T, Wright HL, Satterthwaite AB Molecular Immunology December 2008 46 233-241

Btk and PLCg2 can function independently during B cell development

Halcomb KE, Contreras CM, Coursey TG, Hinman RM, Wright HL, and Satterthwaite AB Eur. J. Immunol. April 2007 37 1033-42

Btk regulates multiple stages in the development and survival of B-1 cells

Contreras CM, Halcomb KE, Randle L, Hinman RM, Gutierrez T, Clarke SH, and Satterthwaite AB Mol. Immunol. April 2007 44 2719-28

B cell receptor signaling down-regulates forkhead box transcription factor class O 1 mRNA expression via phosphatidylinositol 3-kinase and Brutons tyrosine kinase.

Hinman RM, Bushanam JN, Nichols WA, and Satterthwaite AB J. Immunol. January 2007 178 740-7

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Honors/Awards

  • Southwestern Medical Foundation Scholar in Biomedical Research
    UT Southwestern (2000)
  • Leukemia and Lymphoma Society Special Fellowship
    (1998)
  • Irvington Institute for Immunological Research Postdoctoral Fellowship
    (1994)

Professional Associations/Affiliations

  • American Association of Immunologists