Education

Undergraduate
University of Oklahoma Norman (1999)
Graduate School
UT Southwestern Medical Center (2006)

Research Interest

  • Basic Radiation Biology
  • Cellular Response to DNA Damage
  • Intrinsic and Tumor/Cancer Radioresponses
  • The Role of Aberrant DNA Repair and Signaling in Cancer Etiology
  • The Role of the DNA-PK Complex in the Cellular Response to DNA Damage

Publications

Featured Publications LegendFeatured Publications

Lysines 3241 and 3260 of DNA-PKcs are important for genomic stability and radioresistance.
Mori E, Davis AJ, Hasegawa M, Chen DJ Biochem. Biophys. Res. Commun. 2016 Jun
LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair.
Liu XS, Chandramouly G, Rass E, Guan Y, Wang G, Hobbs RM, Rajendran A, Xie A, Shah JV, Davis AJ, Scully R, Lunardi A, Pandolfi PP Nat Commun 2015 6 8325
Scanning fluorescence correlation spectroscopy techniques to quantify the kinetics of DNA double strand break repair proteins after ?-irradiation and bleomycin treatment.
Abdisalaam S, Davis AJ, Chen DJ, Alexandrakis G Nucleic Acids Res. 2014 Jan 42 1 e5
Complex DSBs: A need for resection.
Davis AJ, Chen DJ Cell Cycle 2014 13 24 3796-7