Anwarul Ferdous, Ph.D.

Assistant Professor

Department: Internal Medicine

Biography

Anwarul Ferdous is an Assistant Professor in Internal Medicine in the division of Cardiology. He graduated from Tokyo Institute of Technology in Japan with a PhD degree in 1996. From 1997-1999 he was a lecturer in the Department of Biomolecular Engineering and Biotechnology at the same institution.

He was a postdoctoral researcher in the Center for Biomedical Invention, department of Internal Medicine at UT Southwestern from 1999-2005. He then worked as an Assistant Professor in the Cardiology division of Internal Medicine from 2005-2007. For a short time he worked as an Assistant Professor in the Division of Cardiology at the University of Minnesota, Minneapolis. He returned to UT Southwestern in 2009.

Education

Undergraduate Dhaka University (1986), Biochemistry
Graduate School Dhaka University (1987), Biochemistry
Graduate School Tokyo Institute of Tech (1996), English

Research Interests

  • Genetic manipulation of cell and mouse to evaluate the biological function of a gene
  • Mechanism of transcriptional regulation of gene expression
  • Regulation of transcriptional activity of transactivators by post-translational modifications

Publications

Featured Publications Legend

Featured Publications

Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo.

Ferdous A, Caprioli A, Iacovino M, Martin CM, Morris J, Richardson JA, Latif S, Hammer RE, Harvey RP, Olson EN, Kyba M, Garry DJ Proc Natl Acad Sci U S A. January 2009 2009 Jan 20;106(3) 814-9

Phosphorylation of the Gal4 DNA-binding domain is essential for activator mono-ubiquitylation and efficient promoter occupancy.

Ferdous A, ONeal M, Nalley K, Sikder D, Kodadek T, Johnston SA. Mol Biosyst. November 2008 2008 Nov;4(11) 1116-25

Physical and functional interactions of monoubiquitylated transactivators with the proteasome.

Archer CT, Burdine L, Liu B, Ferdous A, Johnston SA, Kodadek T J Biol Chem. August 2008 2008 Aug 1;283(31) 21789-98

Phosphorylation and mono-ubiquitination of the Gal4 DNA-binding domain are essential for efficient promoter occupancy

Ferdous, A., ONeal, M., Nalley, K., Sikder, D., Johnston, S. A. and Kodadek Mol. Biosys 2008 11 1116-1125

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Honors/Awards

  • March of Dime-Basil Oconner Starter
    Scholar Research Award (2009-2012)
  • Lillihei Heart Institute Endowed Scholar
    (2007)
  • Beginning Grant-in-Aid
    American Heart Institute (1996-1998)
  • Monbusho Scholarship from 1993-1996
    The Ministry of Education, Science and Culture of Japan (1993-1996)
  • Deans honour award of 1983 and 1984 of Dhaka University
    (1983)