Meet Dr. Pradeep Mammen
Heart Failure Specialist

Pradeep Mammen, M.D., finds great satisfaction in his dual role as a clinician-scientist at UT Southwestern Medical Center: As a clinician, he contributes directly to his patients’ health in the clinic, and as a scientist, he pioneers new treatments in the research lab.

Dr. Mammen is an expert in advanced heart failure, ventricular assist devices (VADs), and heart transplantation. He has a special interest in neuromuscular cardiomyopathy – heart failure caused by neuromuscular disorders – and he serves as the Medical Director of UT Southwestern’s dedicated Neuromuscular Cardiomyopathy Clinic, which he founded in 2010. It remains one of only a handful of dedicated neuromuscular cardiomyopathy clinics in the United States.

Meanwhile, Dr. Mammen is one of only 500 cardiologists in the nation who is board certified in advanced heart failure/transplant cardiology. He also performs cardiopulmonary stress testing – a specialized test for advanced heart failure – as well as procedures such as heart biopsies and cardiac catheterizations.

On the research side, Dr. Mammen is the Director of Translational Research for the Advanced Heart Failure Program and investigates the molecular mechanisms underlying heart failure. The goal of his molecular cardiology laboratory is to develop novel therapeutic approaches for the treatment of patients with heart failure. Dr. Mammen’s laboratory is funded through grants from the National Institute of Health and the American Heart Association.

He is optimistic about the future of heart-failure treatment.

“Heart failure, ventricular assist devices, and cardiac transplantation are some of the fastest-growing subspecialties within cardiology,” he says. “And fields like regenerative biology and stem-cell transplantation are enabling us to look at ways to regenerate heart tissue – which helps damaged hearts repair themselves.”

Dr. Mammen is also proud to belong to UT Southwestern’s group of experienced and skilled specialists, a team that includes physicians and surgeons as well as clinicians such as nurse coordinators and practitioners.

“Everything the heart failure/transplant team does, we do as a team – not as individuals – and our patients really benefit from that,” Dr. Mammen says. “UT Southwestern wouldn’t have the excellent heart transplantation survival rates it does if it weren’t for this well-oiled machine, and I’m proud that as a group, we’re able to give these very sick patients another chance at life.”