Paul Blount, Ph.D.

Professor

Department: Physiology

Graduate Programs: Molecular Biophysics, Molecular Microbiology

Biography

Dr. Blount's research is aimed at determining molecular, biochemical, and biophysical mechanisms underlying an organisms’ ability to detect mechanical forces. Such mechanosensation is necessary not only in our sense of touch, but in the ear for hearing and balance, as well as cardiovascular regulation. Because of its tractability and simplicity, he has primarily studied mechanosensitive channels in bacteria.

Dr. Blount’s laboratory utilizes a multidisciplinary approach that includes microbial genetics, biochemical, biophysical and electrophysiological approaches to explore the general functional principles of biological mechanosensors.

His work has also recently expanded to include investigating the potential use of bacterial mechanosensors as potential drug targets, developing them into ‘triggered nanovalves’ that could be used in drug-release devices or “smart” contrasts for MRI, and the biophysical characterization of candidate mammalian mechanosensitive channels.

Education

Undergraduate University of California-San Diego (1983)
Graduate School Washington University (1990)

Research Interests

  • Bacterial channels
  • Mechanosensation
  • mechanosensitive channels
  • Microbial homeostasis
  • Osmoregulation

Publications

Featured Publications Legend

Featured Publications

Results 1-10 of 54

Books

Featured Books Legend

Featured Books

Professional Associations/Affiliations

  • Member of the American Society for Microbiology
  • Member of the Biophysical Society