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Dr. Burstein received his medical degree from Cayetano Heredia University in Lima, Peru.  He completed his Internal Medicine residency training at UT Southwestern Medical School and a Gastroenterology fellowship at the University of Michigan Medical School.  Thereafter, he was also a research fellow at the Vaccine Research Center at the National Institutes of Health.  After completion of his training, he joined the Faculty at University of Michigan (2001-2008), and was later recruited to UT Southwestern, joining the Departments of Internal Medicine (Division of Digestive and Liver Diseases) and Molecular Biology. Dr. Burstein′s research interests include the molecular regulation of the inflammatory response, particularly in the intestinal tract, and ubiquitination events targeting the NF-kB transcription factor.  


Medical School
Cayetano Heredia Peruvian University (1994)
UT Southwestern Medical Center (1998), Internal Medicine
University of Michigan Hospitals & Health Centers (2001), Gastroenterology

Specialty Areas

Clinical Interest

  • Crohn's Disease
  • Inflammatory Bowel Disease (IBD)
  • Ulcerative Colitis

Research Interest

  • COMMD proteins
  • Inflammation, particularly in the intestinal tract
  • NF-kB regulation


Featured Publications LegendFeatured Publications

Regulation of NF-kappaB activity by competition between RelA acetylation and ubiquitination.
Li H, Wittwer T, Weber A, Schneider H, Moreno R, Maine GN, Kracht M, Schmitz ML, Burstein E. Oncogene February 2012 31 5
A bimolecular affinity purification method under denaturing conditions for rapid isolation of a ubiquitinated protein for mass spectrometry analysis
Maine GN, Zaidi IW, Li H, Basrur V, Elenitoba-Johnson K, Burstein E. Nature Protocols August 2010 5 8 1447-1459
XIAP is copper binding protein deregulated in Wilson′s disease and other copper toxicosis disorders
Mufti AR, Burstein E, Csomos RA, Graf TCF, Wilkinson JC, Dick RD, Challa M, Son JK, Bratton SB, Su GL, Brewer GJ, Jakob U, Duckett CS Molecular Cell March 2006 21 6 775-785

Honors & Awards

  • Member
    The American Society for Clinical Investigation (ASCI) (2012)
  • Helmsley Scholar
    Crohn’s and Colitis Foundation of America (2010)
  • AGA Research Scholar Award
    Foundation for Digestive Health and Nutrition (2003)
  • John S. Miller Award
    Outstanding Performance as a House Officer, UT Southwestern Medical School (1998)
  • Valedictorian
    Medical School of Cayetano Heredia University (1994)