Biography

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Dr. Chun-Li Zhang received his Ph.D. in Genetics and Development from UT Southwestern Medical Center, where he worked on transcriptional control of muscle development and heart disease. Upon graduation in 2003, he conducted postdoctoral research as a HHMI Fellow of the Life Sciences Research Foundation in Dr. Ronald Evans’ laboratory at the Salk Institute, La Jolla, California. In collaboration with Dr. Fred Gage at the same institute, Dr. Zhang worked on adult neural stem cells and neurogenesis. In 2008, he joined the faculty as an Assistant Professor at UT Southwestern. The major focus of his laboratory is on molecular mechanisms controlling neural stem cells, adult neurogenesis, regeneration of the central nervous system, and cellular reprogramming.

Education

Graduate School Wuhan University - China , Molecular Cell Biology
Graduate School University of Texas Southwestern Med Ctr Dallas (2002), Genetics

Research Interest

  • Epigenetics
  • Neural Stem Cell
  • Regeneration
  • Reprogramming
  • Tumorigenesis

Publications

Featured Publications LegendFeatured Publications

Orphan nuclear receptor TLX regulates astrogenesis by modulating BMP signaling.

Qin S, Niu W, Iqbal N, Smith DK, Zhang CL Front Neurosci 2014 8 74

The nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche.

Zou Y, Niu W, Qin S, Downes M, Burns DK, Zhang CL Mol. Cell. Biol. 2012 Oct

A role of KLF4 in neurogenesis and radial neuronal migration in the developing cerebral cortex.

Qin S, Zhang CL Mol. Cell. Biol. 2012 Aug

SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells.

Shimozaki K, Zhang CL, Suh H, Denli AM, Evans RM, Gage FH J. Biol. Chem. 2012 Feb 287 8 5969-78

Honors & Awards

  • The Ellison Medical Foundation: New Scholar in Aging
    (2011)
  • The Whitehall Foundation: Research Award
    (2010)
  • Winner of NuGEN Innovation Grant Challenge
    (2010)
  • NIH: Director's New Innovator Award
    (2009)
  • Scientist Development Award-American Heart Association
    (2009)
  • W.W.Caruth, Jr. Scholar in Biomedical Research-UT Southwestern
    (2008)
  • HHMI Fellow of the Life Sciences Research Foundation
    (2005)
  • Dean’s Discretionary Award, UT Southwestern Medical Center at Dallas
    (2002)

Professional Associations/Affiliations

  • Endocrinology Society
  • Molecular and Cellular Cognition Society
  • Sigma Xi, the Scientific Research Society
  • Society for Neuroscience