Dr. Chun-Li Zhang received his Ph.D. in Genetics and Development from UT Southwestern Medical Center, where he worked on transcriptional control of muscle development and heart disease. Upon graduation in 2003, he conducted postdoctoral research as a HHMI Fellow of the Life Sciences Research Foundation in Dr. Ronald Evans’ laboratory at the Salk Institute, La Jolla, California. In collaboration with Dr. Fred Gage at the same institute, Dr. Zhang worked on adult neural stem cells and neurogenesis. In 2008, he joined the faculty as an Assistant Professor at UT Southwestern. The major focus of his laboratory is on molecular mechanisms controlling neural stem cells, adult neurogenesis, regeneration of the central nervous system, and cellular reprogramming.


Graduate School Wuhan University - China , Molecular Cell Biology
Graduate School University of Texas Southwestern Med Ctr Dallas (2002), Genetics

Research Interest

  • Epigenetics
  • Neural Stem Cell
  • Regeneration
  • Reprogramming
  • Tumorigenesis


Featured Publications LegendFeatured Publications

Ataxia and Purkinje cell degeneration in mice lacking the CAMTA1 transcription factor.
Long C, Grueter CE, Song K, Qin S, Qi X, Kong YM, Shelton JM, Richardson JA, Zhang CL, Bassel-Duby R, Olson EN Proc. Natl. Acad. Sci. U.S.A. 2014 Jul
TLX: A master regulator for neural stem cell maintenance and neurogenesis.
Islam MM, Zhang CL Biochim. Biophys. Acta 2014 Jun
Reprogramming the fate of human glioma cells to impede brain tumor development.
Su Z, Zang T, Liu ML, Wang LL, Niu W, Zhang CL Cell Death Dis 2014 5 e1463
Methylene blue promotes quiescence of rat neural progenitor cells.
Xie L, Choudhury GR, Wang J, Park Y, Liu R, Yuan F, Zhang CL, Yorio T, Jin K, Yang SH Front Cell Neurosci 2014 8 315

Honors & Awards

  • The Ellison Medical Foundation: New Scholar in Aging
  • The Whitehall Foundation: Research Award
  • Winner of NuGEN Innovation Grant Challenge
  • NIH: Director's New Innovator Award
  • Scientist Development Award-American Heart Association
  • W.W.Caruth, Jr. Scholar in Biomedical Research-UT Southwestern
  • HHMI Fellow of the Life Sciences Research Foundation
  • Dean’s Discretionary Award, UT Southwestern Medical Center at Dallas

Professional Associations/Affiliations

  • Center for Regenerative Science and Medicine (2014)
  • Society for Neuroscience