Education

Undergraduate Cornell University (1997), Biology
Graduate School University of Texas Southwestern Med Ctr Dallas (2002), Cell Biology

Research Interest

  • Breast Cancer
  • Cell motility and invasion
  • Epithelial-to Mesenchymal Transition
  • Metastasis
  • Tumor microenvironment

Publications

Featured Publications LegendFeatured Publications

PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architecture.

Pearson GW, Hunter T Breast Cancer Res. 2009 11 3

Cyclic AMP selectively uncouples mitogen-activated protein kinase cascades from activating signals.

Pearson GW, Earnest S, Cobb MH Mol. Cell. Biol. 2006 Apr 26 8 3039-47

Cell condition-dependent regulation of ERK5 by cAMP.

Pearson GW, Cobb MH J. Biol. Chem. 2002 Dec 277 50 48094-8

ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation.

Pearson G, English JM, White MA, Cobb MH J. Biol. Chem. 2001 Mar 276 11

Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation.

Pearson G, Bumeister R, Henry DO, Cobb MH, White MA J. Biol. Chem. 2000 Dec 275 48