Yunus Emre Tarhan, M.D.

Yunus Emre Tarhan, M.D., is a Clinical Assistant Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of its Division of Hematology and Oncology. His clinical interests include acute care delivery in hospital medicine, hospital-based cancer care, patient education and teaching, and health care policy and equity.

Originally from Turkey, Dr. Tarhan earned his medical degree at Istanbul University. He completed internal medicine residency training at Mass General Brigham's Salem Hospital in Massachusetts and a postdoctoral research fellowship at the University of Chicago.

Dr. Tarhan's research interests include cancer biomarker discovery, the influence of genetics on cardiovascular disease, personalized oncotherapy, and tumor microenvironment.

Dr. Tarhan has contributed to the book Cancer Science, presented his findings at scientific conferences throughout the United States, and published work in various scientific journals.

Certified by the American Board of Internal Medicine, Dr. Tarhan joined the UT Southwestern faculty in 2024.

Personal Note

Outside of work, Dr. Tarhan is a history buff who enjoys reading, learning about the past, and completing online training sessions. In addition, he participates in health missions to Africa and is a founding partner of a company that specializes in patient education and health delivery systems.

Medical School

Istanbul University-Cerrahpasa, Turkey (2014)

Residency

Mass General Brigham Salem Hospital (2020), Internal Medicine

• Acute care delivery in Hospital Medicine
• Cancer biomarker discovery
• Healthcare policy
• Influence of genetics on cardiovascular disease
• Patient education and teaching
• Tumor microenvironment

Featured Publications

Critical Role of Estrogen Receptor Alpha O-Glycosylation by N-Acetylgalactosaminyltransferase 6 (GALNT6) in Its Nuclear Localization in Breast Cancer Cells.

Deng B, Tarhan YE, Ueda K, Ren L, Katagiri T, Park JH, Nakamura Y Neoplasia 2018 Oct 20 10 1038-1044

p53-independent p21 induction by MELK inhibition.

Matsuda T, Kato T, Kiyotani K, Tarhan YE, Saloura V, Chung S, Ueda K, Nakamura Y, Park JH, Oncotarget 2017 Aug 8 35 57938-57947

Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy.

Park JH, Jang M, Tarhan YE, Katagiri T, Sasa M, Miyoshi Y, Kalari KR, Suman VJ, Weinshilboum R, Wang L, Boughey JC, Goetz MP, Nakamura Y Int. J. Oncol. 2016 Aug 49 2 471-8

Morphological Changes, Cadherin Switching, and Growth Suppression in Pancreatic Cancer by GALNT6 Knockdown.

Tarhan YE, Kato T, Jang M, Haga Y, Ueda K, Nakamura Y, Park JH, Neoplasia 2016 May 18 5 265-272

 Featured Books

Critical role of O-glycosylation of estrogen receptor alpha by GALNT6 in breast cancer cells. In Cancer Science

Deng B, Tarhan YE, Ren L, Ueda K, Katagiri T, Park JH, Nakamura Y. (2018). Hoboken, NJ, Wiley

• American Association for Cancer Reserarch
• American College of Physicians
• American Medical Association
• American Society of Clinical Oncology
• Society of Hospital Medicine