Dr. Ranganathan serves as Director of the Cecil H. and Ida Green Center for Systems Biology at UT Southwestern. 

He received his BS degree in bioengineering at the University of California, Berkeley, and his MD and PhD degrees from the University of California, San Diego, where he studied the mechanisms of visual transduction with Charles Zuker. His conducted postdoctoral work on voltage-gated potassium channels as a Life Sciences Research Foundataion fellow at Harvard Medical School with Roderick MacKinnon, and on protein x-ray crystallography at the Salk Institute for Biological Studies with Joseph Noel.


Univ of California-Berkeley (1985), Bioengineering
Graduate School
University of California-San D (1992), Biology
Medical School
University of California-San D (1994), Medicine

Research Interest

  • cellular signaling networks
  • protein structure, function and dynamics


Featured Publications LegendFeatured Publications

Systems analysis of the single photon response in invertebrate photoreceptors.
Pumir A, Graves J, Ranganathan R, and Shraiman BI. PNAS, in press. 2008
Biochemistry. Signaling across the cell membrane.
Ranganathan R. Science 2007 318(5854) 1253-4
Dynamic scaffolding in a G protein-coupled signaling system.
Mishra P, Socolich M, Wall MA, Graves J, Wang Z, Ranganathan R. Cell 2007 131(1) 80-92
Signal transduction pathway of TonB-dependent transporters.
Ferguson AD, Amezcua CA, Halabi NM, Chelliah Y, Rosen MK, Ranganathan R, Deisenhofer J. PNAS 2007 104(2) 513-8
Knowledge-based potentials in protein design.
Poole AM, Ranganathan R. Curr Opin Struct Biol. 2006 16(4) 508-13

Honors & Awards

  • Cecil H. and Ida Green Chair in Biomedical Science
  • Edward Mallickrodt, Jr. Foundation Scholar