Beatriz Dias, Ph.D. Assistant Instructor School Medical School Department Internal Medicine Biography Beatriz Dias, Ph.D., is an Assistant Instructor in the Department of Internal Medicine at UT Southwestern and a member of its Division of Infectious Diseases and Geographic Medicine. Dr. Dias holds a bachelor's degree in biological sciences from the Federal University of Bahia in Brazil. She earned her master's degree in biotechnology in health and investigative medicine and her doctoral degree in experimental pathology at the Instituto Gonçalo Moniz (Fiocruz Bahia). While in Brazil, Dr. Dias' research focused on investigating the mechanisms underlying the interaction between Leishmania parasites and macrophages, mainly focusing on understanding autophagy's role in Leishmania infection. In 2020, she relocated to the United States to further develop her scientific skills and receive advanced training through a postdoctoral fellowship in Dr. Michael Shiloh's lab at UT Southwestern. A cell biologist passionate about the cell host-pathogen interaction encompassing various aspects from cell biology to in vivo experiments, Dr. Dias joined the UT Southwestern faculty in 2024. Dr. Dias' research goal is to unravel the role of the retromer complex component SNX5 in Mycobacterium tuberculosis antigen presentation and anti-tuberculous host defense. Her efforts have resulted in peer-reviewed publications and reviews. Outside the lab, Dr. Dias likes practicing yoga, traveling, reading, watching TV shows. Research Interest Cell Biology Immunology Infectious diseases Microbiology Publications Featured Publications Pathogenicity and virulence of Mycobacterium tuberculosis. Rahlwes KC, Dias BRS, Campos PC, Alvarez-Arguedas S, Shiloh MU, Virulence 2023 Dec 14 1 2150449 Leishmania infantum Defective in Lipophosphoglycan Biosynthesis Interferes With Activation of Human Neutrophils. Quintela-Carvalho G, Goicochea AMC, Mançur-Santos V, Viana SM, Luz YDS, Dias BRS, Lázaro-Souza M, Suarez M, de Oliveira CI, Saraiva EM, Brodskyn CI, Veras PT, de Menezes JPB, Andrade BB, Lima JB, Descoteaux A, Borges VM, Front Cell Infect Microbiol 2022 12 788196 17-AAG-Induced Activation of the Autophagic Pathway in Leishmania Is Associated with Parasite Death. Petersen ALOA, Cull B, Dias BRS, Palma LC, Luz YDS, de Menezes JPB, Mottram JC, Veras PST, Microorganisms 2021 May 9 5 Betulinic Acid Exerts Cytoprotective Activity on Zika Virus-Infected Neural Progenitor Cells. Cavalcante BRR, Aragão-França LS, Sampaio GLA, Nonaka CKV, Oliveira MS, Campos GS, Sardi SI, Dias BRS, Menezes JPB, Rocha VPC, Rossi EA, Paredes BD, Martins GLS, Allahdadi KJ, Peixoto LR, Barbosa-Filho JM, Souza BSF, Soares MBP, Front Cell Infect Microbiol 2020 10 558324 A docking-based structural analysis of geldanamycin-derived inhibitor binding to human or Leishmania Hsp90. Palma LC, Ferreira LFGR, Petersen ALOA, Dias BRS, Menezes JPB, Moreira DRM, Hernandes MZ, Veras PST, Sci Rep 2019 Oct 9 1 14756 Deciphering the Role Played by Autophagy in Leishmania Infection. Veras PST, de Menezes JPB, Dias BRS, Front Immunol 2019 10 2523 In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195. Guedes CES, Dias BRS, Petersen ALOA, Cruz KP, Almeida NJ, Andrade DR, Menezes JPB, Borges VM, Veras PST, Mem Inst Oswaldo Cruz 2018 Feb 113 4 e170345 Autophagic Induction Greatly Enhances Leishmania major Intracellular Survival Compared to Leishmania amazonensis in CBA/j-Infected Macrophages. Dias BRS, de Souza CS, Almeida NJ, Lima JGB, Fukutani KF, Dos Santos TBS, França-Cost J, Brodskyn CI, de Menezes JPB, Colombo MI, Veras PST, Front Microbiol 2018 9 1890 Results 1-8 of 8 1 Honors & Awards Texas Tuberculosis Research SymposiumTexas Biomedical Research Institute (2023) Travel AwardBrazilian Society of Immunology (2018) Exemplary posterPoster Session
