Meet Dr. Matthias Peltz

Matthias Peltz, M.D., would like to knock heart disease off its perch. It has been the leading killer of patients nationwide for far too long, he says.

We have a broad portfolio of therapies that we can offer to patients with end-stage heart disease. We are second to none in the region.”

Dr. Peltz, Assistant Professor of Cardio Thoracic Surgery and Surgical Director of Cardiac Transplant at UT Southwestern, is a board-certified cardiothoracic surgeon and treats patients with surgical heart disease. He is especially interested in coronary artery bypass grafting and heart transplantation.  He is also an active participant in the UT Southwestern Lung Transplantation Program.

Dr. Peltz is involved in all aspects of transplantation: evaluating candidates, procuring organs, performing surgery, and providing follow-up care. His research on organ preservation could even increase the number of donor hearts that are available for transplant. 

“I’m researching how to support the donor heart better during storage to see if we can use hearts that we typically don’t take,” Dr. Peltz says. “If we can increase the donor supply, this therapy can be offered to more patients.” 

The future for patients with end-stage heart disease is promising, Dr. Peltz says. Patients will have more options, from transplants to the various types of heart assist devices that increasingly are available, he says. 

In the meantime, patients should eat right, eliminate all risk factors within their control, such as smoking, and start an exercise program. Heart disease is sure to drop in the ranks if patients do their part, he says.

Clinical Interests/Specialties


  • Heart transplantation
  • Lung transplantation

End-Stage Heart Disease

  • Aortic valve disease
  • Ischemic heart disease
  • Heart failure

Coronary Artery Bypass Grafting