Kathleen Wilson, M.D.

Dr. Kathleen S. Wilson is the Director of the Cytogenomic Microarray Analysis (CMA) laboratory in the Department of Pathology.  She completed her undergraduate education at Amherst College and graduated with honors in 1986. She received her medical degree in 1991 from The University of Texas Southwestern Medical Center at Dallas. She subsequently completed pathology residency and genetics fellowship training also at U.T. Southwestern.  

Dr. Wilson is on the faculty of the Department of Pathology and the McDermott (Genetics) Center for Human Growth and Development. She is board-certified by the American Board of Pathology (ABP) in Clinical Pathology and the American Board of Medical Genetics (ABMG) in Clinical Cytogenetics.  She is also a fellow of the College of American Pathologists (CAP) and the American College of Medical Genetics (ACMG).   She is a member of the Cytogenetics Resource Committee (CyRC) of the CAP and ACMG, which is involved with setting national policy for cytogenetics by developing accreditation guidelines and issuing proficiency testing. She has served as chair of the Economics of Genetic Services Committee for ACMG and is actively involved nationally in policy related to reimbursement for high complexity genetic testing, with a particular focus on microarray issues. Dr. Wilson’s interest and experience in cytogenetics and molecular cytogenetics have been longstanding with recent publications in Genetics in Medicine and Genes Chromosomes and Cancer, and book chapters in Abeloff: Clinical Oncology, 4th ed. and Clinical Laboratory Hematology, 3rd ed.  Dr. Wilson has won teaching awards and has been actively involved in the teaching and mentorship of medical and graduate students, house staff and junior faculty for the past fifteen years.

Medical School	UT Southwestern Medical Center (1991)
Internship	University of Texas Southwestern (1992), Pathology
Residency	University of Texas Southwestern (1994), Pathology
Fellowship	University of Texas Southwestern (1995), Hematopathology
Fellowship	University of Texas Southwestern (1997), Cytogenetics

• My research interests are focused on the role the clinical genetic diagnostic technologies of conventional cytogenetic analysis, fluorescence in situ hybridization and cytogenomic microarray analysis play in elucidating the pathogenetic events of both constitutional and acquired (neoplastic) disorders.

Featured Publications

College of American Pathologists/American College of Medical Genetics proficiency testing for constitutional cytogenomic microarray analysis.

Brothman AR, Dolan MM, Goodman BK, Park JP, Persons DL, Saxe DF, Tepperberg JH, Tsuchiya KD, Van Dyke DL, Wilson KS, Wolff DJ, Theil KS. Genet in Med 2011 13 765-769.

PARK2 copy number aberrations in two children presenting with autism spectrum disorder: Further support of an association and possible evidence for a new microdeletion/microduplication syndrome.

Scheuerle A and Wilson K. Am J Med Genet Part B Neuropsychiatr Genet 2011 156B 413-420.

The interface of Medicare coverage decision-making and emerging molecular-based laboratory testing.

Burken MI, Wilson KS, Heller K, Pratt VM, Schoonmaker MM, Seifter E. Genet in Med 2009 11 225-231.

High-resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis.

Paulson V, Chandler G, Rakheja D, Galindo R, Wilson K, Amatruda JF, Cameron S. Genes Chromosom Cancer 2011 50 397-408.

A bcr3/short form PML/RARα transcript in an acute promyelocytic leukemia resulted from a derivative chromosome 17 due to submicroscopic insertion of PML gene into RARα locus.

Wang H-Y, Ding J, Vasef MA, Wilson KS. Am J Clin Path 2009 131 64-71.

An extranodal nasal natural killer/T-cell lymphooma with isochromosome 7q10 as the sole cytogenetic aberration was initially diagnosed via bone marrow biopsy.

Wang H-Y, Wilson KS, McKenna RW, Karandikar N, Xu Y. Arch Pathol Lab Med 2007 131 1709-1714.

Immunophenotypic identification of acute myeloid leukemia with monocytic differentiation.

Xu Y, McKenna RW, Wilson KS, Karandikar NJ, Schultz RA, Kroft SH. Leukemia 2006 20 1321-1324.

HER-2 fluorescence in situ hybridization: results from the survey program of the College of American Pathologists.

Persons DL, Tubbs RR, Cooley LD, Dewald GW, Dowling PK, Du E, Mascarello JT, Rao KW, Wilson KS, Wolff DJ, Habegger-Vance G. Arch Pathol Lab Med 2006 130 325-331.

Primary effusion lymphomas (PEL) exhibit complex and recurrent cytogenetic abnormalities.

Wilson KS, McKenna RW, Kroft SH, Dawson DB, Ansari Q, Schneider NR. Br J Haematol 2002 116 113-121.

Chronic myelogenous leukemia [review].

Willis MS and Wilson KS. Lab Med 2002 33 203-207.

• Outstanding Teacher in Genetics: Pre-Clinical Teaching Award
  UT Southwestern Class of 2015 (2012)
• Guide to America's Top Pathologists
  Consumers' Research Council of America (2007-present) (2007)
• Outstanding Teacher in Pathology
  UT Southwestern Class of 2009 (2007)
• Small Group Teaching Award in Pathology
  UT Southwestern Class of 2009 (2007)
• Favorite Teacher Recognition in Pathology
  UT Southwestern Class of 2007 (2005)
• Guide to America's Top Physicians
  Consumers' Research Council of America (2004-present) (2004)
• Amherst College: Graduation with Honors
  B.A., magna cum laude (1986)
• Aston L. Clarke Research Fellowship
  UT Southwestern Medical Center at Dallas (1985)

• American College of Medical Genetics (2002)
• College of American Pathologists (1993)
• American Medical Association (1991)
• Dallas County Medical Society (1991)
• Texas Medical Association (1991)