Tsinghua University (2008), Chemistry
Graduate School
Tsinghua University (2012), Life Sciences


Featured Publications LegendFeatured Publications

Triazoles inhibit cholesterol export from lysosomes by binding to NPC1.
Trinh MN, Lu F, Li X, Das A, Liang Q, De Brabander JK, Brown MS, Goldstein JL Proc. Natl. Acad. Sci. U.S.A. 2016 Dec
Structural biology of intramembrane proteases: mechanistic insights from rhomboid and S2P to ?-secretase.
Sun L, Li X, Shi Y Curr. Opin. Struct. Biol. 2016 Jan 37 97-107
Crystal structure of a phosphorylation-coupled vitamin C transporter.
Luo P, Yu X, Wang W, Fan S, Li X, Wang J Nat. Struct. Mol. Biol. 2015 Feb
Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies.
Condon SM, Mitsuuchi Y, Deng Y, Laporte MG, Rippin SR, Haimowitz T, Alexander MD, Kumar PT, Hendi MS, Lee YH, Benetatos CA, Yu G, Kapoor GS, Neiman E, Seipel ME, Burns JM, Graham MA, McKinlay MA, Li X, Wang J, Shi Y, Feltham R, Bettjeman B, Cumming MH, Vince JE, Khan N, Silke J, Day CL, Chunduru SK J. Med. Chem. 2014 Apr

Honors & Awards

  • Tri-Institutional (Memorial Sloan Kettering Cancer Research Center, Rockefeller University and Weill Cornell Medicine) Breakout Prize for Junior Investigators
  • The Gordon and Betty Moore Foundation Fellow of the Life Sciences Research Foundation
  • C.H. Li Memorial Scholar Fund Award, Rockefeller University

Professional Associations/Affiliations

  • Department of Molecular Genetics, UT Southwestern Medical Center (2017)
  • Laboratory of Cell Biology, The Rockefeller University, New York, NY (2012-2017)
  • School of Life Sciences, Tsinghua University, Beijing, China (2012-2012)
  • School of Life Sciences, Tsinghua University, Beijing, China (2008-2012)
  • Department of Chemistry, Tsinghua University, Beijing, China (2004-2008)