Biography

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Dr. Baojin Ding obtained his M.D. from Medical College of Qingdao University, China and his Ph.D. from Louisiana State University, LA. Upon graduation in 2010, he started postdoctoral trainings in the laboratories of Drs. Daniel Kilpatrick and Vivian Budnik at University of Massachusetts Medical School, Worcester, MA. Using yeast, fly and mammalian cells as model systems, he published many studies on molecular mechanisms of transcription-coupled DNA repair and transcriptional regulations in maturing neurons. His most recent work in Dr. Budnik’s lab revealed a conserved mRNA nuclear export pathway-nuclear envelope budding in mammals. In 2016, Dr. Ding joined the faculty as an Assistant Instructor and worked with Dr. Chun-Li Zhang. His main research interest is on nucleocytoplasmic transport in human neurological diseases. Defective nucleocytoplasmic transport has emerged as a common molecular underpinning of many neurological disorders including neurodegenerative diseases. Using directly reprogrammed neurons from human skin fibroblasts of both patients and healthy controls, Dr. Ding will systematically examine nuclear transport function and identify molecular defects especially those mislocalized RNAs in human disease neurons. These studies will provide novel insights into pathology of neurological disorders and potentially lead to molecular targets for therapeutic interventions.

Education

Undergraduate
Qingdao Medical College (2001), Medicine
Graduate School
Wenzhou Medical College (2004), Clinical Laboratory Science
Graduate School
Louisiana State Univ & A&M Col (2010), Biochemistry

Research Interest

  • Human neurological diseases
  • Neural regeneration and reprogramming
  • Nucleocytoplasmic transport
  • Spatiotemporal regulation of gene expression in neurodevelopment

Publications

Featured Publications LegendFeatured Publications

How to assist parents of children with autism spectrum disorders in rural area?
Ding B J Neurosci Rural Pract 2015 Oct-Dec 6 4 465-6
Consensus Paper: Cerebellar Development.
Leto K, Arancillo M, Becker EB, Buffo A, Chiang C, Ding B, Dobyns WB, Dusart I, Haldipur P, Hatten ME, Hoshino M, Joyner AL, Kano M, Kilpatrick DL, Koibuchi N, Marino S, Martinez S, Millen KJ, Millner TO, Miyata T, Parmigiani E, Schilling K, Sekerková G, Sillitoe RV, Sotelo C, Uesaka N, Wefers A, Wingate RJ, Hawkes R Cerebellum 2015 Oct
Gene expression in maturing neurons: regulatory mechanisms and related neurodevelopmental disorders.
Ding B Sheng Li Xue Bao 2015 Apr 67 2 113-33
Chromatin immunoprecipitation assay of brain tissues using Percoll gradient-purified nuclei.
Ding B, Kilpatrick DL Methods Mol. Biol. 2013 1018 199-209
Lentiviral vector production, titration, and transduction of primary neurons.
Ding B, Kilpatrick DL Methods Mol. Biol. 2013 1018 119-31

Books

Featured Books Legend Featured Books

Lentiviral Vector Production, Titration, and Transduction of Primary Neurons. In Neural Development Methods and Protocols

Baojin Ding and Daniel L. Kilpatrick (2013). Humana Press

Honors & Awards

  • Alzheimer’s Disease Research Award
    (2017)
  • American Association of Anatomists Travel Award
    (2014)
  • American Association of Anatomists Travel Award
    (2013)
  • American Society for Microbiology Postdoctoral Research Fellowship Program
    (2010)
  • Guang Hua Scholarship
    (2003)
  • Excellent Student Award (1997, 1999)
  • Undergraduate Scholarship (1997, 1998, 2000)

Professional Associations/Affiliations

  •  American Society for Cell Biology (2017)
  •  Society for Neuroscience (2014)
  •  American Society for Microbiology (2009-2012)