Education

Graduate School Yale University (1969), Cell Biology
Graduate School Yale University (1975), Cell Biology

Research Interest

  • Cellular and molecular mechanisms of cell-cell fusion
  • Cilium-generated signaling and intraflagellar transport
  • Malaria vaccines
  • Regulation of ciliary membrane protein composition by cilium-generated signaling
  • The biology of cilia and flagella

Publications

Featured Publications LegendFeatured Publications

Fertilization: a sticky sperm protein in plants.
Dresselhaus T, Snell WJ Curr. Biol. 2014 Feb 24 4 R164-6
Organelle Size: A Cilium Length Signal Regulates IFT Cargo Loading.
Pan J, Snell WJ Curr. Biol. 2014 Jan 24 2 R75-8
Regulated Membrane Protein Entry into Flagella Is Facilitated by Cytoplasmic Microtubules and Does Not Require IFT.
Belzile O, Hernandez-Lara CI, Wang Q, Snell WJ Curr. Biol. 2013 Jul
Activation loop phosphorylation of a protein kinase is a molecular marker of organelle size that dynamically reports flagellar length.
Cao M, Meng D, Wang L, Bei S, Snell WJ, Pan J Proc. Natl. Acad. Sci. U.S.A. 2013 Jul 110 30 12337-42
Comparative genomics in Chlamydomonas and Plasmodium identifies an ancient nuclear envelope protein family essential for sexual reproduction in protists, fungi, plants, and vertebrates.
Ning J, Otto TD, Pfander C, Schwach F, Brochet M, Bushell E, Goulding D, Sanders M, Lefebvre PA, Pei J, Grishin NV, Vanderlaan G, Billker O, Snell WJ Genes Dev. 2013 May 27 10 1198-215
A molecular reporter of organelle size: Activation loop phosphorylation of a protein kinase dynamically reports flagellar length.
Cao, M, Meng, D, Wang, L, Bei, S, *Snell, WJ and *Pan, J (*Co-corresponding authors) P. N. A. S. 2013 000 In Press
Development. Plant gametes do fertilization with a twist.
Snell WJ Science 2012 Nov 338 6110 1038-9
Evolutionarily conserved Delta(25(27))-olefin ergosterol biosynthesis pathway in the alga Chlamydomonas reinhardtii.
Miller MB, Haubrich BA, Wang Q, Snell WJ, Nes WD J. Lipid Res. 2012 Aug 53 8 1636-45
The phosphorylation state of an aurora-like kinase marks the length of growing flagella in Chlamydomonas.
Luo M, Cao M, Kan Y, Li G, Snell W, Pan J Curr. Biol. 2011 Apr 21 7 586-91
The ciliary membrane.
Rohatgi R, Snell WJ Curr. Opin. Cell Biol. 2010 Aug 22 4 541-6