Dean Smith, M.D., Ph.D.

Professor

Professor

Department: Pharmacology, Neuroscience

Graduate Programs: Cell Regulation, Neuroscience

Biography

BS University of Utah

MD University of Utah College of Medicine, 1986.

PhD (Biology, Neuroscience) University of California at San Diego, 1992.

HHMI Postdoctoral Fellow UCSD, 1992

Assistant Professor, PEPR fellowship UT Southwestern 1993-1995.

Currently Professor of Pharmacology and Neuroscience, UTSW.

Research Interests: Biochemical and neuronal mechanisms mediating olfactory behavior. We are using a combination of genetics, biochemistry, electrophysiology, cell biology and molecular biology to undertake a molecular dissection of chemosensory behavior in Drosophila. This relatively simple model system allows us to correlate expression of signal transduction molecules with specific subsets of olfactory neurons so we can understand chemical information processing by the brain. Most recently we have been focusing on pheromone signal transduction and how these special odorants elicit behavioral responses.

 

Education

Undergraduate University of Texas Southwestern Med Ctr Dallas (), Neuroscience
Medical School University of Utah (1986)
Graduate School University of California-Berkeley (1992)

Research Interests

  • Olfactory Signal Transduction Mechanisms
  • Pheromone-Induced Behavior

Publications

Featured Publications Legend

Featured Publications

Activation of the T1 neuronal circuit is Necessary and Sufficient to Induce Sexually Dimorphic Behaviors in Drosophila

Ronderos, D. and Smith, D. P. Journal of Neuroscience February 2010 30(7) 2595-2599

SNMP is a Signaling Component Required for Pheromone Sensitivity in Drosophila

Jin, X., Ha, T. S., Smith, D. P. PNAS USA 2008 105 10996-1001

A Pheromone Receptor Mediates 11-cis-Vaccenyl Acetate Responses in Drosophila

Ha, T.-S., Smith, D.P. J. Neuroscience 2006 26 8727-8733

Novel Genomic cDNA Hybrids Produce Effective RNA Interference in Adult Drosophila

Kalidas, S. and Smith, D. P. Neuron 2002 33 1-8

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Books

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Featured Books

Honors/Awards

  • Elected to SWAT
    Member UT Southwestern Academy of Teachers (2009)
  • British Royal Entomological Society Award
    Award for best manuscript published in Insect Molecular Biology (2004)
  • American Heart Association, LBJ Award
    Award for best grant (1995)