Jerry Shay, Ph.D.

Professor

Endowed Title: The Southland Financial Corporation Distinguished Chair in Geriatrics

Department: Cell Biology

Graduate Programs: Cancer Biology, Genetics and Development

Biography

Jerry W. Shay Professor

EDUCATION/TRAINING

 The University of Texas at Austin, BA, Zoology/ Cell Biology, 1966

The University of Kansas at Lawrence, MA, Cell Biol. & Physiol.Mol. Cell., 1968

The University of Colorado at Boulder, PhD, Develop. Biology, 1972-1975

 

POSITIONS AND EMPLOYMENT

1975-1993 Assistant/Associate Professor, Department of Cell Biology/Neuroscience, UT Southwestern

1993- Professor, Department of Cell Biology, UT Southwestern, Southland Financial Corporation Distinguished Chair in Geriatric Research

2002- Associate Director, Education and Training, UT Southwestern Harold Simmons Comprehensive Cancer Center

PANELS

1990-1994 Member, NIH Study Section on Mammalian Genetics

1995-1997 Susan G. Komen Breast Cancer Foundation Research Grant Committee

1996- present Mary Kay Ash Foundation, Chairman, Scientific Review Committee

 

SCIENTIFIC ADVISORY BOARDS/CONSULTATIONS

2002- present Reata Pharmaceutical, Dallas, TX (SAB)

2012- present KAU University, Center for Excellence in Medical Genetics Research, Jeddah Saudi Arabia (Chair, SAB)

 

 

EDITORIAL BOARDS

In Vitro, Cellular and Developmental Biology; Methods in Cell Science; Differentiation; International Journal of Molecular Medicine and Oncology; Experimental Gerontology; Antiaging Research; Mechanisms of Aging and Development: Aging Research Reviews; J. Clinical Pathology; Neoplasia; J. National Cancer Institute; Clinical Cancer Research; J. Regenerative Medicine.

 

AWARDS

1978-1983 NIH Research Career Development Award

1995-1997 AlliedSignal Award for Research on Aging

1997 Institute for Scientific Research - Most highly cited researchers

1996-2003 Ellison Medical Foundation Senior Scholar

2001 American Aging Association, Hayflick Award

2005-2008 Ted Nash Award

 

CURRENT INTERNAL COMMITTEES

1996- Senior Leadership Committee UT Southwestern Simmons Comprehensive Cancer Center

1997-present Executive Committee UTSW/MD Anderson Lung Cancer SPORE

 

 

 

 

US PATENTS

#5,489,508 Issue date: 02/06/96

"Therapy and Diagnosis of Conditions Related to Telomere Length and/or Telomerase Activity"

 #5,639,613 Issue data: 06/17/97

"Methods for Cancer Diagnosis and Prognosis"

 #5,645,986 Issue date: 07/08/97

"Telomerase Activity Inhibitor Screening"

 #5,648,215 Issue date: 07/15/97

"Telomerase Diagnostic Methods"

 #5,686,245 Issue date: 11/11/97

"Screening for Agents that Modulate Telomere Length"

 #5,686,306 Issue date: 11/11/97

"Methods and Reagents for Lengthening Telomeres"

#5,693,474 Issue date: 12/2/97

"Methods for Cancer Diagnosis and Prognosis"

#5,695,932 Issue date: 12/9/97

"Telomerase Activity Assays for Diagnosing Pathogenic Infections and Identifying Pathogen Telomerase Inhibitors"

 #5,707,795 Issue date: 1/13/98

"Diagnosis of Conditions Related to Telomere Length"

#5,830,644 Issue date: 11/3/98

"Method for Screening for Agents which Increase Telomerase Activity in a Cell"

Education

Graduate School University of Texas at Austin (1968)
Graduate School University of Kansas Main Campus (1972)

Research Interests

  • Cancer stem cells
  • Cell Biology of the cancer genome
  • Mechanisms of cellular immortalization
  • Mouse models of radiation-induced cancer
  • Role of telomeres and telomerase in cancer and aging

Publications

Featured Publications Legend

Featured Publications

Two and three dimensional models for risk assessment of radiation-enhanced colorectal turmorigenesis

Roig, A. I. , Hight, S.K., and Shay, J.W. Radiation Research Fall 2008 in press

Actions of human telomerase beyond telomeres

Y-S Cong, J.W. Shay Cell Research Spring 2008 18 725-732

Adult-onset pulmonary fibrosis caused by mutations in telomerase

Tsakiri, K.D., Cronkite, J.T., Kuan, P.J. Xing, C., Ganesh, R., Weissler, J.C., Rosenblatt, R.L. Shay, J.W. Garcia, C.K PNAS Spring 2007 104 7552-7557

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Honors/Awards

  • Univeristy of Texas Health Science Education
    Elected Member (2012)
  • University of Texas Regent's Outstanding Teaching Award
    Medal (2012)
  • Doctor of the Decade (1995-2005)
    Ranked 6th Most Cited Author in General Biomedical Sicence (2006)
  • Ted Nash Award
    Aging Research (2006)
  • Hayflick Award
    American Aging Association (2001)
  • Southland Financial Corporation
    Distinguished Chair in Geriatric Research (2001)
  • Ellison Medical Foundation
    Senior Scholar Award (1999)