Biography

Dr. Park received both his undergraduate and graduate degrees in Electrical Engineering. His doctoral work at Stanford University was focused on technical developments of magnetic resonance imaging (MRI) and spectroscopic imaging (MRSI) with application to preclinical glioma brain tumor metabolism. Following completion of his Ph.D. in 2012, he broadened his research into advanced biomedical imaging as a postdoctoral research fellow and a research associate in the Department of Radiology at Stanford School of Medicine. 

His research interests have built around 1) the development of novel noninvasive molecular imaging tools to elucidate in vivo metabolism and function of normal and pathological states, 2) the identification of characteristics in metabolic diseases, and 3) the application to translational and clinical investigation.

Education

Graduate School
Stanford University (2009), Electrical Engineering
Graduate School
Stanford University (2012), Electrical Engineering

Research Interest

  • Cancer metabolism
  • Development of hyperpolarized MR spectroscopic imaging methods
  • Metabolic imaging agents
  • Molecular imaging of metabolic diseases
  • Noninvasive assessment of cellular metabolism and tissue characteristics
  • Quantitative neuroimaging techniques

Publications

Featured Publications LegendFeatured Publications

Hyperpolarized Sodium [1-(13)C]-Glycerate as a Probe for Assessing Glycolysis in Vivo.
Park JM, Wu M, Datta K, Liu SC, Castillo A, Lough H, Spielman DM, Billingsley KL J. Am. Chem. Soc. 2017 May
Real-time in vivo detection of H2O2 using hyperpolarized 13C-thiourea.
Wibowo A, Park JM, Liu SC, Khosla C, Spielman DM ACS Chem. Biol. 2017 Apr
In vivo assessment of intracellular redox state in rat liver using hyperpolarized [1-(13) C]Alanine.
Park JM, Khemtong C, Liu SC, Hurd RE, Spielman DM Magn Reson Med 2017 Mar
Metabolite-selective hyperpolarized (13)C imaging using extended chemical shift displacement at 9.4T.
Yang S, Lee J, Joe E, Lee H, Choi YS, Park JM, Spielman D, Song HT, Kim DH Magn Reson Imaging 2016 May 34 4 535-40
Hyperpolarized (13) C-lactate to (13) C-bicarbonate ratio as a biomarker for monitoring the acute response of anti-vascular endothelial growth factor (anti-VEGF) treatment.
Park JM, Spielman DM, Josan S, Jang T, Merchant M, Hurd RE, Mayer D, Recht LD NMR Biomed 2016 May 29 5 650-9
Volumetric spiral chemical shift imaging of hyperpolarized [2-(13) c]pyruvate in a rat c6 glioma model.
Park JM, Josan S, Jang T, Merchant M, Watkins R, Hurd RE, Recht LD, Mayer D, Spielman DM Magn Reson Med 2016 Mar 75 3 973-84
Hyperpolarized 13C NMR observation of lactate kinetics in skeletal muscle.
Park JM, Josan S, Mayer D, Hurd RE, Chung Y, Bendahan D, Spielman DM, Jue T J. Exp. Biol. 2015 Oct 218 Pt 20 3308-18
Assessing inflammatory liver injury in an acute CCl4 model using dynamic 3D metabolic imaging of hyperpolarized [1-(13) C]pyruvate.
Josan S, Billingsley K, Orduna J, Park JM, Luong R, Yu L, Hurd R, Pfefferbaum A, Spielman D, Mayer D NMR Biomed 2015 Oct
The feasibility of assessing branched-chain amino acid metabolism in cellular models of prostate cancer with hyperpolarized [1-(13)C]-ketoisocaproate.
Billingsley KL, Park JM, Josan S, Hurd R, Mayer D, Spielman-Sun E, Nishimura DG, Brooks JD, Spielman D Magn Reson Imaging 2014 Sep 32 7 791-5
Dynamic metabolic imaging of hyperpolarized [2-(13) C]pyruvate using spiral chemical shift imaging with alternating spectral band excitation.
Josan S, Hurd R, Park JM, Yen YF, Watkins R, Pfefferbaum A, Spielman D, Mayer D Magn Reson Med 2014 Jun 71 6 2051-8

Honors & Awards

  • Clinical Research Grant Award - "In Vivo Imaging of Traumatic Brain Injury Metabolism"
    The Texas Institute of Brain Injury and Repair (2017-2018)
  • Grant Award - "Imaging Mitochondrial Function in Brain of Patients with Mobility Disorders"
    The Mobility Foundation (2017-2018)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2016-2016)
  • Gambhir-RSL Grant
    Stanford University (2015-2016)
  • Junior Fellow
    International Society of Magnetic Resonance in Medicine (2014-2014)
  • Summa Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2014-2014)
  • Magna Cum Laude Award
    International Society of Magnetic Resonance in Medicine (2013-2013)
  • Radiology Department Research Funding Award
    Stanford University (2013-2014)
  • Cambridge Culture Foundation Fellowship
    Graduate Scholarship (2007-2009)

Professional Associations/Affiliations

  • International Society of Magnetic Resonance in Medicine (2009)