Download Curriculum Vitae

Dr. Rosenfeld attended college at Emory University and graduated from Emory University School of Medicine. He completed his general training in Pediatrics at Yale-New Haven Medical Center and Albert Einstein College of Medicine, where he also was Chief Resident. He then spent a year as a Pediatric Pulmonary Fellow with Amile Scarpelli, MD, PhD at Albert Einstein, followed by 2 yrs in the Perinatal Research Program at the University of Colorado Health Sciences Center under the mentoring of Frederick Battaglia, MD and Giacomo Meschia, MD. After joining the faculty at UT Southwestern in 1973, Dr. Rosenfeld established a perinatal biology laboratory for the study of cardiovascular changes in pregnancy, and in particular, the study of uteroplacental and umbilicoplacental blood flows. He has received nearly continuous funding from NIH for his studies of the mother and fetus for 32 yrs, as well as other grants, making contributions to our understanding of cardiovascular changes in pregnancy and during fetal and neonatal development. He was the Director of the Division of Neonatal-Perinatal Medicine for nearly 35 yrs and has provided research training and mentoring for more than 15 fellows in his specialty, 5 in Maternal-Fetal Medicine, and numerous postdoctoral and medical students. His publication record exceeds 150 peer-reviewed articles and chapters in several textbooks. Dr Rosenfeld was the 2005 recipient of the Founders Award given by the Southern Society for Pediatric Research for his research contributions to child health and was elected a Fellow in the Section of Heart and Circulatory Physiology, American Physiological Society in 2005.


Medical School
Emory University School of Medicine (1966)
Yale-New Haven Hospital (1967), Pediatrics
Albert Einstein Medical Center (1969), Pediatrics
Albert Einstein Medical Center (1970), Pediatrics
Bronx Municipal Hospital Ctr. (1971), Cardiopulmonary
University of Colorado Health Sciences Center (1973), Neonatal-perinatal Medicine

Specialty Areas

Clinical Interest

  • Fetal Growth, Effects on Adult Disease
  • Infection & Diagnosis
  • Patent Ductus Arteriosus (PDA) Closure
  • Placenta Blood Flow Regulation
  • Research Interest

    • Blood pressure regulation before and after birth
    • Cardiovascular role of estrogen in pregnancy
    • Development of the renin-angiotensin system
    • Mechanisms modulating uteroplacental blood flow


    Featured Publications LegendFeatured Publications

    Regulation of the cGMP-cPKG pathway and large- conductance Ca2+-activated K+ channels uterine arteries during the ovine ovarian cycle.
    Khan L, Rosenfeld CR, Liu X, Magness RR. Am J Physiol Endocrin Metabol, 2010 298 E222-E228
    Large conductance Ca+2-activated K+ channels contribute to vascular function in nonpregnant human uterine arteries.
    Rosenfeld CR, Word RA, DeSpain K, Liu X-t. Reprod Sciences 2008 15 651-660
    The renin-angiotensin system in conscious newborn sheep: metabolic clearance rate and activity.
    Velaphi SC, DeSpain K, Roy T, and Rosenfeld CR Pediatr Res 2007 61 681-686
    Vascular development beginning in early ovine gestation: carotid smooth muscle function, phenotype and biochemical markers.
    Hutuna, C, Cox BE, Liu X-t, DeSpain, K and Rosenfeld CR Am J Physiol: Regulatory Integrative Comp Physiol 2007 293 323-333

    Honors & Awards

    • SSPR Founders Award
      Recognition for research contributing to improving child health, Southern Society of Pediatric Research (2005)
    • Associate Editor, Reproductive Sciences (JSGI)
      Appointed to the initial Editorial Board; evaluating basic research (1993)
    • George L. Mac Gregor Professorship of Pediatrics - 1993-Present
      Recognition for research contributions in Perinatal Medicine (1993)
    • Associate Editor, Early Human Development
      Responsible for all manuscripts in the Americas (1986)
    • Perinatal Research Society
      Recognition for contributions to studies in pregnancy and development (1981)

    Professional Associations/Affiliations

    • American Academy of Pediatrics
    • American Pediatric Society
    • American Physiologic Society
    • Society for Gynecologic Investigation
    • Society for Pediatric Research