Medical School
University of California, San Diego (1983)
University of Southern California Med. Center-LAC (1984), Pediatrics
University of Southern California Med. Center-LAC (1986), Pediatrics
University of Southern California Med. Center-LAC (1987), Hematology
UT Southwestern - Children's Medical Center (1990), Pediatric Hematology/oncology

Specialty Areas

Clinical Interest

  • Bone Marrow Failure - Congenital & Acquired
  • Hematology
  • Iron Overload
  • Sickle Cell Disease
  • Transfusion Therapy
  • Research Interest

    • Characterization of the natural history and improvement of the treatment of children and adolescents with non-malignant hematologic diseases such as congenital bone marrow failure syndromes, aplastic anemia thalassemia, sickle cell disease, and immune cytopenias
    • Development of optimum management approaches to major clinical events in children with sickle cell disease (febrile illness, chest syndrome, painful crisis, avascular necrosis, stroke)
    • Use of hydroxyurea, transfusion, stem cell transplantation and other therapies, particularly in young children, to prevent the morbidity of sickle cell anemia


    Featured Publications LegendFeatured Publications

    Pharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia.
    Estepp JH, Melloni C, Thornburg CD, Wiczling P, Rogers Z, Rothman JA, Green NS, Liem R, Brandow AM, Crary SE, Howard TH, Morris MH, Lewandowski A, Garg U, Jusko WJ, Neville KA J Clin Pharmacol 2016 Mar 56 3 298-306
    Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial.
    Ware RE, Davis BR, Schultz WH, Brown RC, Aygun B, Sarnaik S, Odame I, Fuh B, George A, Owen W, Luchtman-Jones L, Rogers ZR, Hilliard L, Gauger C, Piccone C, Lee MT, Kwiatkowski JL, Jackson S, Miller ST, Roberts C, Heeney MM, Kalfa TA, Nelson S, Imran H, Nottage K, Alvarez O, Rhodes M, Thompson AA, Rothman JA, Helton KJ, Roberts D, Coleman J, Bonner MJ, Kutlar A, Patel N, Wood J, Piller L, Wei P, Luden J, Mortier NA, Stuber SE, Luban NL, Cohen AR, Pressel S, Adams RJ Lancet 2015 Dec
    Organ iron accumulation in chronically transfused children with sickle cell anaemia: baseline results from the TWiTCH trial.
    Wood JC, Cohen AR, Pressel SL, Aygun B, Imran H, Luchtman-Jones L, Thompson AA, Fuh B, Schultz WH, Davis BR, Ware RE Br. J. Haematol. 2015 Nov
    Effects of hydroxyurea treatment for patients with hemoglobin SC disease.
    Luchtman-Jones L, Pressel S, Hilliard L, Brown RC, Smith MG, Thompson AA, Lee MT, Rothman J, Rogers ZR, Owen W, Imran H, Thornburg C, Kwiatkowski JL, Aygun B, Nelson S, Roberts C, Gauger C, Piccone C, Kalfa T, Alvarez O, Hassell K, Davis BR, Ware RE Am. J. Hematol. 2015 Nov
    Liver iron concentration measurements by MRI in chronically transfused children with sickle cell anemia: Baseline results from the TWiTCH trial.
    Wood JC, Pressel S, Rogers ZR, Odame I, Kwiatkowski JL, Lee MT, Owen WC, Cohen AR, St Pierre T, Heeney MM, Schultz WH, Davis BR, Ware RE Am. J. Hematol. 2015 Jun
    Guidelines for the Standard Monitoring of Patients With Thalassemia: Report of the Thalassemia Longitudinal Cohort.
    Tubman VN, Fung EB, Vogiatzi M, Thompson AA, Rogers ZR, Neufeld EJ, Kwiatkowski JL J. Pediatr. Hematol. Oncol. 2015 Apr 37 3 e162-9


    Featured Books Legend Featured Books

    Honors & Awards

    • Best Pediatric Specialists in Dallas
      D Magazine (2015-2016)
    • Mom-Approved Doctor
      Child Magazine (2015)
    • Physician Scientist Award, Fellow
      Damon Runyon-Walter Winchell Cancer Research Fund (1990-1993)
    • American Cancer Society
      Texas Division Oncology, Research Fellowship (1989)
    • Phi Beta Kappa
      Alpha of California (1978)

    Professional Associations/Affiliations

    • American Society of Hematology (1990)
    • American Society of Pediatric Hematology/Oncology (1989)
    • American Academy of Pediatrics (1987)
    • American Pediatric Society
    • Society for Pediatric Research