Milo Lin, Ph.D.
Assistant Professor
Endowed Title Cecil H. and Ida Green Endowed Scholar in Biomedical Computational Science
School Medical School
Department Lyda Hill Department of Bioinformatics | Biophysics | Center for Alzheimer's and Neurodegenerative Diseases
Graduate Programs Biomedical Engineering, Molecular Biophysics
Biography
Since 2021, Milo Lin has been appointed as assistant professor in the Lyda Hill Department of Bioinformatics. Since 2015, he is also a member of the Cecil H. and Ida Green Center for Systems Biology. He is the Cecil H. and Ida M. Green Endowed Scholar in Biomedical Computational Science. Milo Lin received his B.S. and Ph.D. in physics from Caltech in 2006 and 2012, respectively. His thesis work, under the mentorship of Ahmed Zewail, was on physical principles of protein folding. He was a Miller Independent Research Fellow, hosted by David Chandler, at UC Berkeley from 2012-2015.
Education
- Undergraduate
- California Inst of Technology (2006), Physics
- Graduate School
- California Inst of Technology (2012), Physics
Research Interest
- Using statistical physics, interpretable deep learning, and molecular simulations, the Lin lab seeks design principles that constrain and modularize the behavior of biological systems. Current projects in the lab include predicting and designing information flow and allostery within proteins, generating truly de novo protein sequences for specified functions, and mapping biomolecular dynamics to the mathematical domain of scalable electronic circuits.
Publications
Featured Publications
- Protein aggregates thermodynamically order regardless of sequence.
- Nielsen AW, Sari L, Fraser R, Lin MM, Proteins 2023 May 91 5 705-711
- Explainable neural networks that simulate reasoning
- Paul J. Blazek, Milo M. Lin Nat Comp Sci 2021 1 607-618
- Circuit Reduction of Heterogeneous Nonequilibrium Systems
- Milo M. Lin PRL 2020 125 218101
- Hydrophobic forces and the length limit of foldable protein domains.
- Lin MM, Zewail AH Proc. Natl. Acad. Sci. U.S.A. 2012 Jun 109 25 9851-6
- Full Publication List
Honors & Awards
- Clauser Doctoral Prize
Best PhD thesis over all fields as judged by originality and potential intellectual impact (2012-2012) - Miller Research Fellow
Independent postdoctoral fellow hosted at UC Berkeley (2012-2015)
Professional Associations/Affiliations
- Center for Alzheimer's and Neurodegenerative Diseases (2016)
- Dept. of Biophysics (2015)
- Green Center for Systems Biology (2015)
- Lyda Hill Department of Bioinformatics (2021)