Biography

Wenxin Zheng, M.D., Professor of Pathology, Obstetrics and Gynecology, American board certified pathologist, graduated from Shanghai Medical College Fudan University and trained at Columbia University, Cornell University, and Brown University Medical Centers in anatomic pathology and gynecologic pathology, Selected by US News and World Report in 2013 as one of America's top pathologists, Dr. Zheng is an internationally recognized gynecologic pathologist with outstanding expertise in every aspect of gynecologic pathology.  Dr. Zheng’s main research contributions include endometrial serous carcinogenesis and precancerous lesion endometrial glandular dysplasia, cell origin of low-grade ovarian serous carcinoma, hormonal etiology of ovarian epithelial cancers, and tubal contribution of ovarian endometriosis and its associated ovarian cancers.

Education

Medical School
Shanghai Medical College of Fudan University (1982)
Internship
Hospital of Obstetrics and Gynecology (1983), Obstetrics & Gynecology
Residency
Hospital of Obstetrics and Gynecology (1986), Obstetrics & Gynecology
Fellowship
Columbia University (1989), Molecular Reproduction
Residency
Cornell New York Presbyterian Hospital (1995), Pathology
Fellowship
Brown University Woman & Infant Hospital (1996), Gynecologic Pathology

Research Interest

  • Biomarkers to aid the diagnosis of gynecologic cancers
  • Cervical cancer: suitable model of cervical cancer screening, effective intervention, and prevention in developing countries.
  • Endometrial serous carcinoma: carcinogenesis, early detection and prevention
  • Ovarian cancer early detection and prevention
  • Tubal origin of ovarian endometriosis and its related cancer development
  • Tubal secretory cell biology

Publications

Featured Publications LegendFeatured Publications

Association between human papillomavirus type 16 E6 and E7 variants with subsequent persistent infection and recurrence of cervical high-grade squamous intraepithelial lesion after conization.
Zhang L, Yang B, Zhang A, Zhou A, Yuan J, Wang Y, Sun L, Cao H, Wang J, Zheng W J. Med. Virol. 2016 Apr
Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway.
Wang Y, Wang Y, Zhang Z, Park JY, Guo D, Liao H, Yi X, Zheng Y, Zhang D, Chambers SK, Zheng W Oncotarget 2016 Jan
Fallopian tube secretory cell expansion: a sensitive biomarker for ovarian serous carcinogenesis.
Wang Y, Li L, Wang Y, Tang SN, Zheng W Am J Transl Res 2016 8 1 230-8
Overexpression and oncogenic function of HMGA2 in endometrial serous carcinogenesis.
Wei L, Liu X, Zhang W, Wei Y, Li Y, Zhang Q, Dong R, Kwon JS, Liu Z, Zheng W, Kong B Am J Cancer Res 2016 6 2 249-59
Cytologic studies of the fallopian tube in patients undergoing salpingo-oophorectomy.
Chen H, Klein R, Arnold S, Chambers S, Zheng W Cancer Cell Int. 2016 16 78
Ovarian serous carcinogenesis from tubal secretory cells.
Zhang W, Wei L, Li L, Yang B, Kong B, Yao G, Zheng W Histol. Histopathol. 2015 Jul 11645
Are clear cell carcinomas of the ovary and endometrium phenotypically identical? A proteomic analysis.
Fata CR, Seeley EH, Desouki MM, Du L, Gwin K, Hanley KZ, Hecht JL, Jarboe EA, Liang SX, Parkash V, Quick CM, Zheng W, Shyr Y, Caprioli RM, Fadare O Hum. Pathol. 2015 Jun
Primary sources of pelvic serous cancer in patients with endometrial intraepithelial carcinoma.
Jia L, Yuan Z, Wang Y, Cragun JM, Kong B, Zheng W Mod. Pathol. 2015 Jan 28 1 118-27
Tubal origin of ovarian endometriosis and clear cell and endometrioid carcinoma.
Wang Y, Mang M, Wang Y, Wang L, Klein R, Kong B, Zheng W Am J Cancer Res 2015 5 3 869-79
Flutamide and biomarkers in women at high risk for ovarian cancer: preclinical and clinical evidence.
Gruessner C, Gruessner A, Glaser K, AbuShahin N, Zhou Y, Laughren C, Wright H, Pinkerton S, Yi X, Stoffer J, Azodi M, Zheng W, Chambers SK Cancer Prev Res (Phila) 2014 Sep 7 9 896-905