Dr. Yan Peng completed her Pediatric Residency/Chief Resident at Beijing Medical University Hospitals and practiced there as a Pediatric Nephrologist for two years. After a combined six years of basic research on kidney disease at Mayo Clinic, Rochester, MN and UT-Southwestern Medical Center (UTSW), Dallas, TX, she went to University of Pittsburgh Medical Center (UPMC) for her Pathology Residency. Upon the completion, she took two fellowship trainings in Breast and Gynecologic Pathology at UPMC and Cytopathology at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, respectively.
She has been a Breast and Gynecologic Pathologist and Cytopathologist at UT Southwestern Medical Center. She is the Pathology Liaison at Cancer Committee of UTSW Simmons Cancer Center and University Hospital. She had served as Medical Directors of Diagnostic Immunohistochemistry Laboratory and Tumor Biomarker Image Analysis Laboratory at one of UTSW teaching hospitals for 10 years. As co-investigator, she has participated in more than 30 National Cancer Institute (NCI) Breast and Gynecologic cancer clinical trials.
She has published 70 peer-reviewed articles and served as an editorial board member for multiple scientific journals.
- Medical School
- Beijing Medical University (1986)
- Beijing University Hospital (1989), Pediatrics
- Graduate School
- Beijing Medical University (1991)
- Mayo Clinic (1995), Physiology
- UT Southwestern Medical Center (1999), Molecular Nephrology Research
- University of Pittsburgh Medical Center (2003), Anatomic & Clinical Pathology
- University of Pittsburgh Medical Center Magee Womens Hospital (2004), Breast & Gynecologic Pathology
- Harvard Medical School/Beth Israel Deaconess Medical Center (2005), Cytopathology
- Comprehensive Immunohistochemical Markers including Prognostic Markers
- Evaluation of Breast Tissue for Diagnosis & Treatment Plans
- Biopsy & Cytology Correlation
- Cervical/Endocervical Biopsies & Endometrial Curetting
- HPV Hybridization for Cervical & Vulvar Biopsies
- Identification & Quantitation of Infectious Organisms
- Prognostic Markers for Endometrial Carcinomas
- Breast Cancer and Gynecologic Cancer Pathology
- Diagnostic, prognostic and predictive tumor biomarkers
- Novel role of PELP1 in regulating chemotherapy response in mutant p53-expressing triple negative breast cancer cells.
- Krishnan SR, Nair BC, Sareddy GR, Roy SS, Natarajan M, Suzuki T, Peng Y, Raj G, Vadlamudi RK Breast Cancer Res. Treat. 2015 Mar
- Quantification of Human Epidermal Growth Factor Receptor 2 Immunohistochemistry Using the Ventana Image Analysis System: Correlation With Gene Amplification by Fluorescence In Situ Hybridization: The Importance of Instrument Validation for Achieving High (>95%) Concordance Rate.
- Dennis J, Parsa R, Chau D, Koduru P, Peng Y, Fang Y, Sarode VR Am. J. Surg. Pathol. 2015 Jan
- Significantly increased PELP1 protein expression in primary and metastatic triple-negative breast carcinoma (TNBC): comparison with GATA3 expression and PELP1's potential role in TNBC
- Dang D, Raj G, Sarode V, Molberg K, Vadlamudi R and Peng Y* humpath. 2015 46 12 1829-1835
- KIF14 Promotes AKT Phosphorylation and Contributes to Chemoresistance in Triple-Negative Breast Cancer.
- Singel SM, Cornelius C, Zaganjor E, Batten K, Sarode VR, Buckley DL, Peng Y, John GB, Li HC, Sadeghi N, Wright WE, Lum L, Corson TW, Shay JW Neoplasia 2014 Mar 16 3 247-256.e2
- Cutaneous and mammary apocrine carcinomas have different immunoprofiles.
- Piris A, Peng Y, Boussahmain C, Essary LR, Gudewicz TM, Hoang MP Hum. Pathol. 2014 Feb 45 2 320-6
- Modulatory effect of neoadjuvant chemotherapy on biomarkers expression; assessment by digital image analysis and relationship to residual cancer burden in patients with invasive breast cancer.
- Cockburn A, Yan J, Rahardja D, Euhus D, Peng Y, Fang Y, Rumnong Sarode V Hum. Pathol. 2014 Feb 45 2 249-58
- Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes.
- Daniel AR, Gaviglio AL, Knutson TP, Ostrander JH, D'Assoro AB, Ravindranathan P, Peng Y, Raj GV, Yee D, Lange CA Oncogene 2014 Jan
- Ki-67 expression is increased in p16-expressing triple-negative breast carcinoma and correlates with p16 only in p53-negative tumors.
- Sugianto J, Sarode V, Peng Y Hum. Pathol. 2013 Dec
- Roles of p53 and p16 in Triple-negative Breast Cancer (This article was selected to be featured on Oncology Central.)
- Dang D and Peng Y Breast Cancer Management (Future Medicine). 2013 2 6 537-544
- Decreased Androgen Receptor Expression is Associated with Distant Metastases in Patients with Androgen Receptor Expressing Triple-negative Breast Carcinoma.
- Sutton LM, Cao D, Sarode VR, Molberg KH, Torgbe K, Haley B and Peng Y. Am. J Clin. Pathol. 2012 138 511-516 (CME/SAM article)
Invasive Breast Carcinomas. In Peng Y, Kong C, and Chen Y. Practical Breast Pathology. Atkins K and Kong C (eds.), a volume in the Pattern Recognition Series. Kevin O. Leslie and Mark R.Wick (eds.).
Peng Y, Kong C, and Chen Y. (2013; 147-212). Philadelphia, PA, Elsevier
Honors & Awards
- Vice President, North Texas Society of Pathologists (NTSP)
- President-Elect, International Association of Chinese Pathologists (IACP)
- President-Elect, The UTSW Faculty Senate
- Distinguished Young Investigator Award in Medicine
Beijing, China (1993)
- Distinguished Scientist Award of Canada China Child Health Foundation
- Best National Medical Article Award
- Outstanding Medical Student Award and Scholarship
Beijing Medical University (1986)