Meet Dr. Mathew Augustine
Gastrointestinal Cancer Surgeon in Dallas

Surgical oncologist M. Mathew Augustine, M.D., Ph.D., fights gastrointestinal cancer in both the operating room and the laboratory at UT Southwestern Medical Center.

Mathew Augustine, M.D., Ph.D.: Surgical Oncologist

Dr. Augustine uses his surgical expertise to treat patients with pancreatic, liver, bile duct (biliary), and gallbladder cancer. In addition, he also treats other gastrointestinal conditions, both cancerous and benign. These include cysts of the pancreas, pancreatic neuroendocrine tumors (PNETs), gastrointestinal stromal tumors (GISTs), gastric cancer, colon cancer, carcinoid tumors, and retroperitoneal sarcomas. 

Although many patients require traditional open surgery, Dr. Augustine offers minimally invasive techniques such as laparoscopic and robotic surgery in highly selected cases. 

In addition to his surgical expertise, Dr. Augustine is also active in the laboratory as a basic science researcher and is broadening UT Southwestern’s study of gastrointestinal malignancies – critical to developing new and more effective therapies. 

“I hope to understand why patients develop treatment resistance to pancreatic cancer, colon cancer, and gastrointestinal stromal tumor,” he says. “We hope that discoveries related to this work impact all patients undergoing therapy for cancer today.“ 

As a member of the GI Cancer Surgical Team at UT Southwestern, Dr. Augustine offers patients a comprehensive, multidisciplinary approach to cancer care.

“Receiving a diagnosis of cancer charts patients on a long journey during which they are confronted with a myriad of complicated, life-altering choices and decisions,” Dr. Augustine says. 

He has witnessed firsthand the critical role that surgical oncologists play in guiding patients through the decision-making process. 

“We have a dedicated multidisciplinary oncology team, comprising gastroenterologists, medical and radiation oncologists, radiologists, geneticists, pathologists, and surgeons motivated by the same common purpose: to provide patients with a highly personalized, cutting-edge approach to their cancer care,” he says. 

“Patients and their loved ones come to us seeking not only knowledge and direction, but most importantly understanding and hope. I am very fortunate to be among a group of extraordinary individuals dedicated to their care,” Dr. Augustine says.