Featured Publications
Malignant glioma: lessons from genomics, mouse models, and stem cells.
Chen J, McKay RM, Parada LF Cell 2012 Mar 149 1 36-47
Neurofibromin modulates adult hippocampal neurogenesis and behavioral effects of antidepressants.
Li Y, Li Y, McKay RM, Riethmacher D, Parada LF J. Neurosci. 2012 Mar 32 10 3529-39
Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis
Amiri, A., Cho, W., Zhou, J., Birnbaum, S.G., Sinton, C.M., McKay, R.M., and Parada, L.F. Journal of Neuroscience 2012 32(17) 5880-5890
A restricted cell population propagates glioblastoma growth following chemotherapy
Chen, J., Li, Y., Yu, T-S., McKay, R.M., Burns, D.K., and Parada, L.F. Nature 2012 488 522-526
Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle.
Zhou J, Shrikhande G, Xu J, McKay RM, Burns DK, Johnson JE, Parada LF Genes Dev. 2011 Aug 25 15 1595-600
Susceptible Stages in Schwann Cells for NF1-Associated Plexiform Neurofibroma Development.
Le LQ, Liu C, Shipman T, Chen Z, Suter U, Parada LF Cancer Res. 2011 Jul 71 13 4686-95
Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas.
Le LQ, Shipman T, Burns DK, Parada LF Cell Stem Cell 2009 May 4 5 453-63
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model.
Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF Cancer Cell 2009 Jan 15 1 45-56
TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment.
Li Y, Luikart BW, Birnbaum S, Chen J, Kwon CH, Kernie SG, Bassel-Duby R, Parada LF Neuron 2008 Aug 59 3 399-412
Pten haploinsufficiency accelerates formation of high-grade astrocytomas.
Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Parada LF Cancer Res. 2008 May 68 9 3286-94