Research Interest

  • Functional genomics, metabolomics and bioinformatics
  • Genetic and metabolic diseases
  • Translational Research

Publications

Featured Publications LegendFeatured Publications

Mitochondrial biogenesis in erythropoiesis is regulated by mTORC1-mediated protein translation
Liu X*, Zhang Y*, Ni M*, Cao H, Signer RAJ, Li D, Li M, Gu Z, Hu Z, Dickerson KE, Weinberg SE, Chandel NS, DeBerardinis RJ, Zhou F, Shao Z, Xu J Nature Cell Biology 2017 In press
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1 - mutant lung cancer cells
Jiyeon Kim , Zeping Hu , Ling Cai , Kailong Li , Eunhee Choi , Brandon Faubert , Divya Bezwada , Jaime Rodriguez-Canales , Pamela Villalobos , Yu-Fen Lin , Min Ni , Kenneth Huffman , Luc Girard , Lauren Byers , Keziban Unsal-Kacmaz , Christopher Peña , John Heymach , Els Wauters , Johan Vansteenkiste , Diego Castrillon , Benjamin Chen , Ignacio Wistuba , Diether Lambrechts , Jian Xu , John Minna, Ralph J DeBerardinis 2017 In press
Metabolic Heterogeneity in Human Lung Tumors.
Hensley CT, Faubert B, Yuan Q, Lev-Cohain N, Jin E, Kim J, Jiang L, Ko B, Skelton R, Loudat L, Wodzak M, Klimko C, McMillan E, Butt Y, Ni M, Oliver D, Torrealba J, Malloy CR, Kernstine K, Lenkinski RE, DeBerardinis RJ Cell 2016 Feb 164 4 681-94
Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.
Shu S, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M, Huh SJ, Liang Y, Ryan J, Doherty E, Mohammed H, Guo H, Stover DG, Ekram MB, Peluffo G, Brown J, D'Santos C, Krop IE, Dillon D, McKeown M, Ott C, Qi J, Ni M, Rao PK, Duarte M, Wu SY, Chiang CM, Anders L, Young RA, Winer EP, Letai A, Barry WT, Carroll JS, Long HW, Brown M, Liu XS, Meyer CA, Bradner JE, Polyak K Nature 2016 Jan 529 7586 413-7
Importance of Breast Cancer Subtype in the Development of Androgen Receptor Directed Therapy.
Lim E, Ni M, Cao S, Hazra A, Tamimi RM, Brown M Curr Breast Cancer Rep 2014 Jun 6 2 71-78
XBP1 promotes triple-negative breast cancer by controlling the HIF1a pathway.
Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, Song M, Tan C, Landis MD, Ferrari M, Shin SJ, Brown M, Chang JC, Liu XS, Glimcher LH Nature 2014 Apr 508 7494 103-7
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Wey S, Luo B, Tseng CC, Ni M, Zhou H, Fu Y, Bhojwani D, Carroll WL, Lee AS Blood 2012 Jan 119 3 817-25
Inositol 1,4,5-trisphosphate receptor 1 mutation perturbs glucose homeostasis and enhances susceptibility to diet-induced diabetes.
Ye R, Ni M, Wang M, Luo S, Zhu G, Chow RH, Lee AS J. Endocrinol. 2011 Aug 210 2 209-17