Research Interest

  • Functional genomics, metabolomics and bioinformatics
  • Genetic and metabolic diseases
  • Translational Research


Featured Publications LegendFeatured Publications

Importance of Breast Cancer Subtype in the Development of Androgen Receptor Directed Therapy.
Lim E, Ni M, Cao S, Hazra A, Tamimi RM, Brown M Curr Breast Cancer Rep 2014 Jun 6 2 71-78
XBP1 promotes triple-negative breast cancer by controlling the HIF1a pathway.
Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, Song M, Tan C, Landis MD, Ferrari M, Shin SJ, Brown M, Chang JC, Liu XS, Glimcher LH Nature 2014 Apr 508 7494 103-7
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling.
Wey S, Luo B, Tseng CC, Ni M, Zhou H, Fu Y, Bhojwani D, Carroll WL, Lee AS Blood 2012 Jan 119 3 817-25
Inositol 1,4,5-trisphosphate receptor 1 mutation perturbs glucose homeostasis and enhances susceptibility to diet-induced diabetes.
Ye R, Ni M, Wang M, Luo S, Zhu G, Chow RH, Lee AS J. Endocrinol. 2011 Aug 210 2 209-17
PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B.
Baba A, Ohtake F, Okuno Y, Yokota K, Okada M, Imai Y, Ni M, Meyer CA, Igarashi K, Kanno J, Brown M, Kato S Nat. Cell Biol. 2011 Jun 13 6 668-75
Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targeting.
Ni M, Zhang Y, Lee AS Biochem. J. 2011 Mar 434 2 181-8
Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP.
Zhang Y, Liu R, Ni M, Gill P, Lee AS J. Biol. Chem. 2010 May 285 20 15065-75
Transcriptional silencing of {gamma}-globin by BCL11A involves long-range interactions and cooperation with SOX6.
Xu J, Sankaran VG, Ni M, Menne TF, Puram RV, Kim W, Orkin SH Genes Dev. 2010 Apr 24 8 783-98