Featured Publications
Control of stress-dependent cardiac growth and gene expression by a microRNA
Van Rooij, E., Sutherland, L.B., Qi, X., Richardson, J. A., Hill, J., and Olson, E. N. Science 2007 316 575-579
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.
Shin, C.H., Liu, Z.P., Passier, R., Zhang, C.L., Wang, D.Z., Harris, T.M., Yamagishi, H., Richardson, J.A., Childs, G., and Olson, E.N. Cell 2002 110 725-735
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor
Wang, D-Z., Chang, P., Wang, Z., Small, E., Krieg, P. A., and Olson, E. N. Cell 2001 105 851-862
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy.
Molkentin, J.D., Lu, J., Antos, C.L., Markham, B., Richardson, J., Robbins, J., Grant, S., and Olson, E.N. Cell 1998 93 215-228
Control of mouse cardiac morphogenesis and myogenesis by the myogenic transcription factor MEF2C.
Lin, Q., Schwarz, J., Buchana, C., and Olson, E.N. Science 1997 276 1404-1407
Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3ζ.
Patrick, D.M., Zhang, C.C., Huiyu, Y.T., Qi, X., Schwartz, R.J., Huang, L., and Olson, E.N. Genes & Development 2010 24 1614-1619
MicroRNA regulatory networks in cardiovascular development.
Liu, N. and Olson, E.N. Developmental Cell 2010 18 510-525
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.
van Rooij, E., Quiat, D., Johnson, B.A., Sutherland, L.B., Qi, X., Richardson, J.A., Kelm Jr., R.J., and Olson, E.N. Developmental Cell 2009 17 662-673
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice.
Williams, A.H., Valdez, G., Moresi, V., Qi, X., McAnally, J., Elliott, J.L., Bassel-Duby, R., Sanes, J.R., and Olson, E.N. Science 2009 326 1549-1554
MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury.
Xin, M., Small, E.M., Sutherland, L.B., Qi, X., McAnally, J., Plato, C.F., Richardson, J.A., Bassel-Duby, R., and Olson, E.N. Genes & Development 2009 23 2166-2178