Chieko Mineo, Ph.D. Titles and Appointments Professor Schools Medical School | Graduate School Departments Pediatrics | Cell Biology Graduate Programs Genetics, Development and Disease Biography Dr. Chieko Mineo received both her B.S and Ph.D. in Pharmacology from University of Tokyo. She received post-doctoral training in Cell Biology at the University of Texas Southwestern Medical Center. Dr. Mineo joined the faculty in the Department of Pediatrics at the University of Texas Southwestern Medical Center in 2002. She is a member of the Integrative Biology Graduate Program in the Division of Basic Science. Education Undergraduate University of Tokyo (1982), Pharmacology Graduate School University of Tokyo (1992), Pharmacology Research Interest Antiphospholipid Syndrome Insulin resistance and endothelial dysfunction Vascular Biology and Atherosclerosis Publications Endothelial FOXO1 Lactylation: A New Link Between Disturbed Flow and Atherosclerosis Mineo C Circulation research 2026 Mar 138 e328413 Role of the endothelial cell apolipoprotein E receptor 2 in modulating the effects of apoE3 and apoE4 on insulin blood-brain barrier transport Thomas P, Nguyen V, Weaver R, Hansen K, Sacharidou A, Banks WA, Mineo C, Shaul PW, Rhea EM PloS one 2026 Feb 21 Regulation of Insulin Transcytosis Across Endothelium in Metabolic Health and Disease Mineo C, Shaul PW Arteriosclerosis, Thrombosis, and Vascular Biology 2026 Feb 46 e321545 Apolipoprotein E receptor 2 in endothelium promote glucose tolerance by mediating insulin delivery to skeletal muscle Sacharidou A, Chambliss KL, Peng J, Tanigaki K, Islam MN, Sirsi S, Lemoff A, Hoyt K, Mineo C, Shaul PW Molecular Metabolism 2025 Nov 101 The ACTH test fails to diagnose adrenal insufficiency and augments cytokine production in sepsis Hao D, Wang Q, Ito M, Xue J, Guo L, Huang B, Mineo C, Shaul PW, Li XA JCI Insight 2025 Apr 10 27-hydroxycholesterol and endothelial cell immune memory link maternal hypercholesterolemia with atherosclerosis in the offspring: Atherogenesis Mineo C, Shaul PW Nature Cardiovascular Research 2025 Apr 4 350-352 Endothelial SR-B1 is dispensable for thermogenesis but promotes selective cholesterol uptake in brown adipose tissue Hurkmans KM, Heine M, Rinninger F, Jaeckstein MY, Mineo C, Shaul PW, Heeren J Journal of lipid research 2025 66 Elevated free cholesterol levels due to impaired reverse cholesterol transport are a risk factor for polymicrobial sepsis in mice Wang Q, Guo L, Hao D, Ito M, Mineo C, Shaul PW, Li XA Journal of Biological Chemistry 2024 Dec 300 Correction to: 27-Hydroxycholesterol Binds GPER and Induces Progression of Estrogen Receptor-Negative Breast Cancer (Cancers, (2022), 14, 6, (1521), 10.3390/cancers14061521) Avena P, Casaburi I, Zavaglia L, Nocito MC, La Padula D, Rago V, Dong J, Thomas P, Mineo C, Sirianni R, Shaul PW Cancers 2024 Dec 16 Alterations in plasma protein N-glycosylation after caloric restriction and bariatric surgery Štambuk T, Kifer D, Greto VL, Dempster NJ, Cvetko A, Gillies RS, Tomlinson JW, Sgromo B, Mineo C, Shaul PW, Lauc G, Lingvay I, Geremia A, Arancibia-Cárcamo CV Surgery for Obesity and Related Diseases 2024 Jun 20 587-596 Results 1-10 of 101 1 2 3 4 5 Next Last Books Featured Books Mechanisms of Antiphospholipid Antibody-Mediated Pregnancy Morbidity. In Erkan D, Lockshin MD, eds. Antiphospholipid Syndrome: Current Research Highlights and Clinical Insights. Salmon JE, Mineo C, Giles I, Chamley LW, Meroni PL, Abrahams VM. (2017). Springer International Publishing; 117-146. Regulation of eNOS in Caveolae. In Jasmin J, Frank P, Lisanti MP, eds. Caveolins and Caveolae: Roles in Signaling and Disease Mechanisms. Mineo C, Shaul PW. (2012). New York: Springer; 51-62. Professional Associations/Affiliations American Diabetes Association (2006) American Heart Association (2004)
