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Jessica Moreland, M.D.

Jessica Moreland, M.D.

Titles and Appointments

Associate Dean Faculty Development | Associate Dean for Faculty Development

Professor

Endowed Title
Thomas Fariss Marsh, Jr. Chair in Pediatrics
Schools
Medical School | Graduate School
Departments
Faculty Development | Microbiology | Pediatrics
Graduate Programs
Molecular Microbiology

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    Download Curriculum Vitae

    Jessica Moreland received her Bachelor’s Degree in Zoology from Duke University.  She obtained her M.D. from Vanderbilt University in Nashville, Tennessee, in 1992.  Dr. Moreland remained at Vanderbilt University for her residency training in Pediatrics and her fellowship training in Pediatric Critical Care.  After completion of all of her postgraduate training, she was recruited to join the faculty at the University of Iowa.  Dr. Moreland was appointed as an Assistant Professor on the tenure track in 1998 and rose to the rank of Professor with Tenure in 2013. Her research focus has centered broadly on the theme of neutrophil-based inflammation.  While on faculty at the University of Iowa, Dr. Moreland served initially as the fellowship director for Pediatric Critical Care and served as the Division Director prior to joining UT Southwestern.  Dr. Moreland took over as the Division Chief of Pediatric Critical Care at UT Southwestern in January of 2014.  She is currently the Professor of Pediatrics and Microbiology and the Thomas Fariss Marsh, Jr. Chair in Pediatrics.

  • Education
    Medical School
    Vanderbilt University School of Medicine (1992)
    Residency
    Vanderbilt University Medical Center (1995), Pediatrics
    Fellowship
    Vanderbilt University Medical Center (1998), Pediatric Critical Care Medicine
  • Research Interest
    • Inflammation and the resolution of inflammation
    • Mechanisms of toll-like receptor signaling and role of single nucleotide polymorphisms
    • NADPH oxidase and reactive oxygen species signaling
    • Neutrophil priming
    • Translational analysis of neutrophil activation state during cardiopulmonary bypass and during chronic inflammatory disease
  • Publications
    Role for IRAK-4 and p38 in Neutrophil Signaling in Response to Bacterial Lipoproteins from Staphylococcus aureus
    Hook JS, Matheis AD, Kavanaugh JS, Horswill AR, Moreland JG Inflammation 2025 Aug 48 1704-1715
    Does serial procalcitonin monitoring predict clinical outcomes in children with sepsis? A diagnostic stewardship study
    Rubbab B, Davila S, Moreland J, Firmani S, Most Z Antimicrobial Stewardship and Healthcare Epidemiology 2025 Jun 5
    Granular Insights: Neutrophil Predominance and Elastase Release in Severe Asthma Exacerbations in a Pediatric Cohort
    Henley K, Tresselt E, Hook JS, Patel PA, Gill MA, Moreland JG Cells 2024 Mar 13
    Quantifying neutrophil extracellular trap release in a combined infection-inflammation NET-array device
    Datla US, Vundurthy B, Hook JS, Menon N, Razmi Bagtash H, Shihabeddin T, Schmidtke DW, Moreland JG, Radic MZ, Jones CN Lab on a Chip 2024 Jan 24 615-628
    Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation
    Li Y, Hook JS, Ding Q, Xiao X, Chung SS, Mettlen M, Xu L, Moreland JG, Agathocleous M Nature communications 2023 Dec 14
    Itaconate-producing neutrophils regulate local and systemic inflammation following trauma
    Crossley JL, Ostashevskaya-Gohstand S, Comazzetto S, Hook JS, Guo L, Vishlaghi N, Juan C, Xu L, Horswill AR, Hoxhaj G, Moreland JG, Tower RJ, Levi B JCI Insight 2023 Oct 8
    Evaluation of an association between RANKL and OPG with bone disease in people with cystic fibrosis
    Abid S, Lee MJ, Rodich B, Hook JS, Moreland JG, Towler D, Maalouf NM, Keller A, Ratti G, Jain R Journal of Cystic Fibrosis 2023 Jan 22 140-145
    Neutrophil Extracellular Trap Formation Potential Correlates with Lung Disease Severity in COVID-19 Patients
    Kinnare N, Hook JS, Patel PA, Monson NL, Moreland JG Inflammation 2022 Apr 45 800-811
    Novel neutrophil phenotypic signature in pediatric patients with type 1 diabetes and diabetic ketoacidosis
    Nichols BE, Hook JS, Weng K, Ahn C, Moreland JG Journal of Leukocyte Biology 2022 Apr 111 849-856
    Lipoproteins from staphylococcus aureus drive neutrophil extracellular trap formation in a TLR2/1- And PAD-dependent manner
    Hook JS, Patel PA, O'Malley A, Xie L, Kavanaugh JS, Horswill AR, Moreland JG Journal of Immunology 2021 Aug 207 :966-973
  • Honors & Awards
    • Best Pediatric Specialists/Doctors in Dallas
      D Magazine (2015) (2018)
    • Election to American Pediatric Society
      (2013)
    • Best Doctors in America
      Best Doctors, Inc. (2012-2013)
    • Above and Beyond Award
      University of Iowa Health Care (2005-2006)
    • Election to Society for Pediatric Research
      (2001)
    • Elliot V. Newman Award
      Vanderbilt University Medical Center Research Forum (1997)
    • Amos Christie Award in Pediatrics
      Vanderbilt University Medical School (1995)
    • David Karzon Award
      Vanderbilt University, Department of Pediatrics (1995)
    • House Officer Research Award
      Society for Pediatric Research (1995)
    • 1992 Alpha Omega Alpha
      Alpha Omega Alpha Honor Medical Society (1992)
  • Professional Associations/Affiliations
    • American Academy of Pediatrics
    • American Pediatric Society
    • Society for Critical Care Medicine
    • Society for Leukocyte Biology
    • Society for Pediatric Research