Biography

Michael Sebert, M.D., is a graduate of Duke University and the Stanford University School of Medicine. He completed his internship and residency in pediatrics as well as his fellowship in pediatric infectious diseases at the Children's Hospital of Philadelphia.

Dr. Sebert's clinical interests include infection prevention and healthcare-associated infections. He focuses his research on microbial evolution, pathogen transmission and hospital epidemiology.

He is presently an Associate Professor of Pediatrics and serves as the Medical Director for Infection Prevention and Control at Children's Health.

Education

Medical School
Stanford University School of Medicine (1995)
Residency
Children's Hospital of Philadelphia (1998), Pediatrics
Fellowship
Children's Hospital of Philadelphia (2002), Pediatric Infectious Diseases

Specialty Areas

Clinical Interest

  • Human Immunodeficiency Virus (HIV)
  • Otitis Media
  • Pediatric Infectious Disease
  • Respiratory Tract Infections
  • Sinusitis
  • Research Interest

    • Bacterial pathogenesis
    • Genomic epidemiology
    • Hospital epidemiology
    • Microbial evolution
    • Pathogen transmission
    • Streptococcus pneumoniae

    Publications

    Featured Publications LegendFeatured Publications

    Low Utility of the Pediatric Isolator Blood Culture System for the Detection of Fungemia in Children: A Ten Year Review.
    Campigotto A, Richardson SE, Sebert M, McElvania TeKippe E, Chakravarty A, Doern CD J. Clin. Microbiol. 2016 Jun
    Competence in Streptococcus pneumoniae is a response to an increasing mutational burden.
    Gagne AL, Stevens KE, Cassone M, Pujari A, Abiola OE, Chang DJ, Sebert ME PLoS ONE 2013 8 8 e72613
    The HtrA protease from Streptococcus pneumoniae digests both denatured proteins and the competence-stimulating peptide.
    Cassone M, Gagne AL, Spruce LA, Seeholzer SH, Sebert ME J. Biol. Chem. 2012 Nov 287 46 38449-59
    Frequent beneficial mutations during single-colony serial transfer of Streptococcus pneumoniae.
    Stevens KE, Sebert ME PLoS Genet. 2011 Aug 7 8 e1002232
    Competence in Streptococcus pneumoniae is regulated by the rate of ribosomal decoding errors.
    Stevens KE, Chang D, Zwack EE, Sebert ME MBio 2011 2 5
    Bacteriocin activity of Streptococcus pneumoniae is controlled by the serine protease HtrA via posttranscriptional regulation.
    Dawid S, Sebert ME, Weiser JN J. Bacteriol. 2009 Mar 191 5 1509-18
    Severe influenza B myocarditis and myositis.
    Tabbutt S, Leonard M, Godinez RI, Sebert M, Cullen J, Spray TL, Friedman D Pediatr Crit Care Med 2004 Jul 5 4 403-6
    An outbreak of Serratia marcescens bacteremia after general anesthesia.
    Sebert ME, Manning ML, McGowan KL, Alpern ER, Bell LM Infect Control Hosp Epidemiol 2002 Dec 23 12 733-9

    Books

    Featured Books Legend Featured Books

    Honors & Awards

    • DFW Hospital Council Physician of the Year Nominee
      Children's Medical Center (2015)
    • Dean's Award for Research, Stanford University School of Medicine
      (1995)

    Professional Associations/Affiliations

    • Society for Healthcare Epidemiology of America (2014)
    • Society for Pediatric Research (2009)
    • American Academy of Pediatrics (2005)
    • Infectious Disease Society of America (2003)
    • American Society for Microbiology (2000-2014)