MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.
Williams KC, Renthal NE, Condon JC, Gerard RD, Mendelson CR Proc. Natl. Acad. Sci. U.S.A. 2012 May 109 19 7529-34
Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia.
Benlhabib H, Mendelson CR Mol. Cell. Biol. 2011 May 31 10 1949-58
miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor.
Renthal NE, Chen CC, Williams KC, Gerard RD, Prange-Kiel J, Mendelson CR Proc. Natl. Acad. Sci. U.S.A. 2010 Nov 107 48 20828-33
Expression of surfactant protein by the fetal lung signals the initiation of labor
Condon JC, Pancharatnam J, Faust JM, Mendelson CR Proc Natl Acad Sci USA 2004 101 4978-4983
Potential role of nuclear factor kB and reactive oxygen species (ROS) in cAMP and cytokine regulation of surfactant protein-A gene expression in lung type II cells
Islam K, Mendelson CR Mol Endocrinol 2002 16 1428-1440
Regulation of the synthesis of the major surfactant apoprotein in fetal rabbit lung tissue
Mendelson CR, Chen C, Boggaram V, Zacharias C, Snyder JM J Biol Chem 1986 261 9938-9943
Isolation and characterization of a complementary DNA specific for human aromatase cytochrome P-450 mRNA
Evans CT, Ledesma DB, Schulz TZ, Simpson ER, Mendelson CR Proc Natl Acad Sci USA 1986 83 6387-6391
Estrogen-Related Receptor ? (ERR?) Regulates Oxygen-Dependent Expression of Voltage-gated Potassium (K+) Channels and Tissue Kallikrein during Human Trophoblast Differentiation.
Luo Y, Kumar P, Mendelson CR Mol. Endocrinol. 2013 Apr
The c-Myc Regulated microRNA (miR)-17~92 and miR-106a~363 Clusters Target CYP19A1 and hGCM1 to Inhibit Human Trophoblast Differentiation.
Kumar P, Luo Y, Tudela C, Alexander JM, Mendelson CR Mol. Cell. Biol. 2013 Feb
Mice deficient in surfactant protein A (SP-A) and SP-D or in TLR2 manifest delayed parturition and decreased expression of inflammatory and contractile genes.
Montalbano AP, Hawgood S, Mendelson CR Endocrinology 2013 Jan 154 1 483-98