Mala Mahendroo, PhD, is an Associate Professor in the Department of Obstetrics and Gynecology's Division of Basic Reproductive Biology Research and a member of the Cecil H. and Ida Green Center for Reproductive Biology Sciences.
Dr. Mahendroo did her graduate research on the gene regulation of estrogen synthesis in human adipose in the laboratory of Dr. Evan Simpson at UT Southwestern and completed her PhD in 1992. She carried out her postdoctoral project entitled, "Targeted disruption of steroid 5alpha-reductases in mice," in David. W. Russell's laboratory in the Department of Molecular Genetics. Her postdoctoral work was supported by fellowships from the National Institutes of Health, The Lalor Foundation, and the Burroughs Wellcome Foundation. She joined the Department of Obstetrics and Gynecology as an Assistant Professor in 2000.
|Undergraduate||Texas A & M University (1986), Biochemistry|
|Graduate School||University of Texas Southwestern Med Ctr Dallas (1992), Biochemistry|
- Cervical Ripening
- Extracellular Matrix
- Molecular Physiology and Immunology of Reproduction
- Non-coding RNA regulation of cervical ripening
- Pregnancy and Parturition
- Preterm Birth
The molecular mechanisms of cervical ripening differ between term and preterm birth.
Holt, R, Timmons, B, Akgul, Y., Akins, M, Mahendroo, M Endocrinology 2011 152 1036-1046
Cervical softening during pregnancy- regulated changes in collagen cross-linking and composition of matricellular proteins in the mouse.
Akins, M, Luby-Phelps, K., Bank, R., Mahendroo, M Biol. of Reprod 2011 84 1053-62
Second harmonic generation imaging as a potential tool for staging pregnancy and predicting preterm birth.
Akins, M.L., Luby-Phelps, K., Mahendroo, M J of Biomedical Optics 2010 15(2) 026020
Temporal changes in myeloid cells in the cervix during pregnancy and parturition.
Timmons, B.C., Fairhurst, A.M.F., Mahendroo, M J of Immunology 2009 182 2700-2707
Hyaluronan and its binding proteins during cervical ripening and parturition: Dynamic changes in size, distribution and temporal sequence.
Monika Ruscheinsky, Carol De la Motte, Mala Mahendroo Matrix Biology Summer 2008 27 487-497
Zhang Y, Akins ML, Murari K, Xi J, Li MJ, Luby-Phelps K, Mahendroo M, Li X Proc. Natl. Acad. Sci. U.S.A. 2012 Aug 109 32 12878-83
Akgul Y, Holt R, Mummert M, Word A, Mahendroo M Endocrinology 2012 Jul 153 7 3493-503
Holt R, Timmons BC, Akgul Y, Akins ML, Mahendroo M Endocrinology 2011 Mar 152 3 1036-46
Honors & Awards
- Initiative Award
Burroughs Wellcome Preterm Birth Initiative Award 2011 (2011)
- Scholar Award
Hartwell Foundation Scholar - 2010 (2010)
- Career Award
Burroughs Wellcome Career Award 1997 - 2003 (1997)
- Lalor Fellowship Award
Lalor Foundation 1996 - 1997 (1996)
- Research Fellowship Award
NIH National Research Service Award 1993 - 1996 (1993)
- American Association for the Advancement of Science
- Endocrine Society
- Perinatal Research Society
- Society for Gynecologic Investigation
- Society for the Study of Reproduction