Biography

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Mala Mahendroo, PhD, is an Associate Professor in the Department of Obstetrics and Gynecology's Division of Basic Reproductive Biology Research and a member of the Cecil H. and Ida Green Center for Reproductive Biology Sciences.

Dr. Mahendroo did her graduate research on the gene regulation of estrogen synthesis in human adipose in the laboratory of Dr. Evan Simpson at UT Southwestern and completed her PhD in 1992. She carried out her postdoctoral project entitled, "Targeted disruption of steroid 5alpha-reductases in mice," in David. W. Russell's laboratory in the Department of Molecular Genetics. Her postdoctoral work was supported by fellowships from the National Institutes of Health, The Lalor Foundation, and the Burroughs Wellcome Foundation. She joined the Department of Obstetrics and Gynecology as an Assistant Professor in 2000.

Education

Undergraduate Texas A & M University (1986), Biochemistry
Graduate School University of Texas Southwestern Med Ctr Dallas (1992), Biochemistry

Research Interest

  • Cervical Ripening
  • Extracellular Matrix
  • Molecular Physiology and Immunology of Reproduction
  • Non-coding RNA regulation of cervical ripening
  • Pregnancy and Parturition
  • Preterm Birth

Publications

Featured Publications LegendFeatured Publications

A compact fiber-optic SHG scanning endomicroscope and its application to visualize cervical remodeling during pregnancy.

Zhang Y, Akins ML, Murari K, Xi J, Li MJ, Luby-Phelps K, Mahendroo M, Li X Proc. Natl. Acad. Sci. U.S.A. 2012 Aug 109 32 12878-83

Dynamic changes in cervical glycosaminoglycan composition during normal pregnancy and preterm birth.

Akgul Y, Holt R, Mummert M, Word A, Mahendroo M Endocrinology 2012 Jul 153 7 3493-503

The molecular mechanisms of cervical ripening differ between term and preterm birth.

Holt R, Timmons BC, Akgul Y, Akins ML, Mahendroo M Endocrinology 2011 Mar 152 3 1036-46

Honors & Awards

  • Initiative Award
    Burroughs Wellcome Preterm Birth Initiative Award 2011 (2011)
  • Scholar Award
    Hartwell Foundation Scholar - 2010 (2010)
  • Career Award
    Burroughs Wellcome Career Award 1997 - 2003 (1997)
  • Lalor Fellowship Award
    Lalor Foundation 1996 - 1997 (1996)
  • Research Fellowship Award
    NIH National Research Service Award 1993 - 1996 (1993)

Professional Associations/Affiliations

  • American Association for the Advancement of Science
  • Endocrine Society
  • Perinatal Research Society
  • Society for Gynecologic Investigation
  • Society for the Study of Reproduction