Education

Undergraduate
Boston University (1999), Chemistry
Graduate School
Univ of California-Berkeley (2005), Chemistry

Publications

Featured Publications LegendFeatured Publications

Modulation of Esterified Drug Metabolism by Tanshinones from Salvia miltiorrhiza ("Danshen").
Hatfield MJ, Tsurkan LG, Hyatt JL, Edwards CC, Lemoff A, Jeffries C, Yan B, Potter PM J. Nat. Prod. 2013 Jan 76 1 36-44
Lead optimization of antimalarial propafenone analogues.
Lowes D, Pradhan A, Iyer LV, Parman T, Gow J, Zhu F, Furimsky A, Lemoff A, Guiguemde WA, Sigal M, Clark JA, Wilson E, Tang L, Connelly MC, Derisi JL, Kyle DE, Mirsalis J, Guy RK J. Med. Chem. 2012 Jul 55 13 6087-93
Synthesis and evaluation of sulfonylnitrophenylthiazoles (SNPTs) as thyroid hormone receptor-coactivator interaction inhibitors.
Hwang JY, Attia RR, Zhu F, Yang L, Lemoff A, Jeffries C, Connelly MC, Guy RK J. Med. Chem. 2012 Mar 55 5 2301-10
Optimization of propafenone analogues as antimalarial leads.
Lowes DJ, Guiguemde WA, Connelly MC, Zhu F, Sigal MS, Clark JA, Lemoff AS, Derisi JL, Wilson EB, Guy RK J. Med. Chem. 2011 Nov 54 21 7477-85
IDH1 and IDH2 mutations in pediatric acute leukemia.
Andersson AK, Miller DW, Lynch JA, Lemoff AS, Cai Z, Pounds SB, Radtke I, Yan B, Schuetz JD, Rubnitz JE, Ribeiro RC, Raimondi SC, Zhang J, Mullighan CG, Shurtleff SA, Schulman BA, Downing JR Leukemia 2011 Oct 25 10 1570-7
Functional regulation of cystic fibrosis transmembrane conductance regulator-containing macromolecular complexes: a small-molecule inhibitor approach.
Zhang W, Penmatsa H, Ren A, Punchihewa C, Lemoff A, Yan B, Fujii N, Naren AP Biochem. J. 2011 Apr 435 2 451-62
Evaluation of Diarylureas for Activity Against Plasmodium falciparum.
Zhang Y, Anderson M, Weisman JL, Lu M, Choy CJ, Boyd VA, Price J, Sigal M, Clark J, Connelly M, Zhu F, Guiguemde WA, Jeffries C, Yang L, Lemoff A, Liou AP, Webb TR, Derisi JL, Guy RK ACS Med Chem Lett 2010 Dec 1 9 460-465
Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models.
Mallari JP, Zhu F, Lemoff A, Kaiser M, Lu M, Brun R, Guy RK Bioorg. Med. Chem. 2010 Dec 18 23 8302-9
Structural confirmation and quantification of individual ligands from the surface of multi-functionalized gold nanoparticles.
Zhou H, Li X, Lemoff A, Zhang B, Yan B Analyst 2010 Jun 135 6 1210-3
Dual detection approach to a more accurate measure of relative purity in high-throughput characterization of compound collections.
Lemoff A, Yan B J Comb Chem 2008 Sep-Oct 10 5 746-51